[HTML][HTML] The signal pathways and treatment of cytokine storm in COVID-19
L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …
and is more devastating than any other previous infectious disease. It has affected a …
[HTML][HTML] Inflammasome activation at the crux of severe COVID-19
The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), results in life-threatening disease in a minority of patients, especially elderly …
(SARS-CoV-2), results in life-threatening disease in a minority of patients, especially elderly …
[HTML][HTML] Genetic mechanisms of critical illness in COVID-19
Host-mediated lung inflammation is present, and drives mortality, in the critical illness
caused by coronavirus disease 2019 (COVID-19). Host genetic variants associated with …
caused by coronavirus disease 2019 (COVID-19). Host genetic variants associated with …
Predictors of COVID‐19 severity: a literature review
B Gallo Marin, G Aghagoli, K Lavine… - Reviews in medical …, 2021 - Wiley Online Library
Summary The coronavirus disease 2019 (COVID‐19) pandemic is a rapidly evolving global
emergency that continues to strain healthcare systems. Emerging research describes a …
emergency that continues to strain healthcare systems. Emerging research describes a …
[HTML][HTML] An immune-based biomarker signature is associated with mortality in COVID-19 patients
Immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) contribute to disease severity of coronavirus disease 2019 (COVID-19) …
(SARS-CoV-2) contribute to disease severity of coronavirus disease 2019 (COVID-19) …
[HTML][HTML] Biomarkers in COVID-19: an up-to-date review
M Samprathi, M Jayashree - Frontiers in pediatrics, 2021 - frontiersin.org
The ongoing pandemic of coronavirus disease 2019 (COVID-19) poses several challenges
to clinicians. Timely diagnosis and hospitalization, risk stratification, effective utilization of …
to clinicians. Timely diagnosis and hospitalization, risk stratification, effective utilization of …
[HTML][HTML] A potential role of interleukin 10 in COVID-19 pathogenesis
L Lu, H Zhang, DJ Dauphars, YW He - Trends in Immunology, 2021 - cell.com
A unique feature of the cytokine storm in coronavirus disease 2019 (COVID-19) is the
dramatic elevation of interleukin 10 (IL-10). This was thought to be a negative feedback …
dramatic elevation of interleukin 10 (IL-10). This was thought to be a negative feedback …
Tissue-specific immunopathology in fatal COVID-19
Rationale: In life-threatening coronavirus disease (COVID-19), corticosteroids reduce
mortality, suggesting that immune responses have a causal role in death. Whether this …
mortality, suggesting that immune responses have a causal role in death. Whether this …
[HTML][HTML] Viral dynamics and real-time RT-PCR Ct values correlation with disease severity in COVID-19
Real-time RT-PCR is considered the gold standard confirmatory test for coronavirus disease
2019 (COVID-19). However, many scientists disagree, and it is essential to understand that …
2019 (COVID-19). However, many scientists disagree, and it is essential to understand that …
[HTML][HTML] Elevated interleukin-10 levels in COVID-19: potentiation of pro-inflammatory responses or impaired anti-inflammatory action?
Interleukin (IL)-10 is a pleiotropic cytokine known for its potent anti-inflammatory and
immunosuppressive effects. Originally identified as a product of T helper 2 cells, IL-10 is now …
immunosuppressive effects. Originally identified as a product of T helper 2 cells, IL-10 is now …