The immune system plays critical roles in both autoimmunity and cancer, diseases at
opposite ends of the immune spectrum. Autoimmunity arises from loss of T cell tolerance …

Due to their multidirectional influence, adipocytokines are currently the subject of numerous
intensive studies. Significant impact applies to many processes, both physiological and …

Simple Summary The involvement of leptin and adiponectin with receptors in the formation
of many types of cancer as well as their impact on the clinical course of cancer patients are …

Obesity is a disease with high potential for fatality. It perfectly fits the disease definition, as
cancer does. This is because it damages body structure and functions, both mechanically …

Obesity is a complex metabolic condition considered a worldwide public health crisis, and a
deeper mechanistic understanding of obesity-associated diseases is urgently needed …

The percentage of people affected by overweight, obesity and/or diabetes drastically
increased within the last decades. This development is still ongoing, which puts a large part …

Background: The Mediterranean diet is considered one of the dietary patterns with the most
accumulated scientific evidence on health benefits. In children, it has positive effects in the …

Oxidative stress with subsequent premutagenic oxidative DNA damage has been implicated
in colorectal carcinogenesis. The repair of oxidative DNA damage is initiated by lesion …

Global exposures to air pollution and cigarette smoke are novel in human evolutionary
history and are associated with at least 12 million premature deaths per year. We investigate …

Obesity is on the rise worldwide, and consequently, obesity-related non-communicable
diseases are as well. Nutritional overload induces metabolic adaptations in an attempt to …