Virus-like particles: preparation, immunogenicity and their roles as nanovaccines and drug nanocarriers

S Nooraei, H Bahrulolum, ZS Hoseini… - Journal of …, 2021 - Springer
Virus-like particles (VLPs) are virus-derived structures made up of one or more different
molecules with the ability to self-assemble, mimicking the form and size of a virus particle but …

Coronavirus vaccine development: from SARS and MERS to COVID-19

YD Li, WY Chi, JH Su, L Ferrall, CF Hung… - Journal of biomedical …, 2020 - Springer
Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new type of
coronavirus that causes the Coronavirus Disease 2019 (COVID-19), which has been the …

Virus-like particle vaccinology, from bench to bedside

MO Mohsen, MF Bachmann - Cellular & molecular immunology, 2022 - nature.com
Virus-like particles (VLPs) have become key tools in biology, medicine and even
engineering. After their initial use to resolve viral structures at the atomic level, VLPs were …

A universal design of betacoronavirus vaccines against COVID-19, MERS, and SARS

L Dai, T Zheng, K Xu, Y Han, L Xu, E Huang, Y An… - Cell, 2020 - cell.com
Vaccines are urgently needed to control the ongoing pandemic COVID-19 and previously
emerging MERS/SARS caused by coronavirus (CoV) infections. The CoV spike receptor …

Viral targets for vaccines against COVID-19

L Dai, GF Gao - Nature Reviews Immunology, 2021 - nature.com
Vaccines are urgently needed to control the coronavirus disease 2019 (COVID-19)
pandemic and to help the return to pre-pandemic normalcy. A great many vaccine …

Nanoparticle-based strategies to combat COVID-19

R Medhi, P Srinoi, N Ngo, HV Tran… - ACS Applied Nano …, 2020 - ACS Publications
Coronavirus disease 2019 (COVID-19) is the worst pandemic disease of the current
millennium. This disease is caused by the highly contagious severe acute respiratory …

Recent advances in the vaccine development against Middle East respiratory syndrome-coronavirus

CY Yong, HK Ong, SK Yeap, KL Ho… - Frontiers in microbiology, 2019 - frontiersin.org
Middle East respiratory syndrome (MERS) is a deadly viral respiratory disease caused by
MERS-coronavirus (MERS-CoV) infection. To date, there is no specific treatment proven …

MERS-CoV: understanding the latest human coronavirus threat

A Chafekar, BC Fielding - Viruses, 2018 - mdpi.com
Human coronaviruses cause both upper and lower respiratory tract infections in humans. In
2012, a sixth human coronavirus (hCoV) was isolated from a patient presenting with severe …

Nanocarrier vaccines for SARS-CoV-2

J Machhi, F Shahjin, S Das, M Patel… - Advanced Drug Delivery …, 2021 - Elsevier
The SARS-CoV-2 global pandemic has seen rapid spread, disease morbidities and death
associated with substantive social, economic and societal impacts. Treatments rely on re …

Virus-like particle vaccines and platforms for vaccine development

M Kheirvari, H Liu, E Tumban - Viruses, 2023 - mdpi.com
Virus-like particles (VLPs) have gained a lot of interest within the past two decades. The use
of VLP-based vaccines to protect against three infectious agents—hepatitis B virus, human …