Statin-related myopathy is a clinically important cause of statin intolerance and
discontinuation. The spectrum of statin-related myopathy ranges from common but clinically …

HMG-CoA reductase inhibitors ('statins') represent the most effective and widely prescribed
drugs currently available for the reduction of low-density lipoprotein cholesterol, a critical …

Background Statin therapy is a proven effective treatment of hyperlipidemia. However, a
significant number of patients cannot tolerate statins. This study was conducted to review …

Background: Studies demonstrate that lowering low-density lipoprotein cholesterol (LDL-C)
using a statin is associated with significant reduction in cardiovascular events. Whether visit …

The term statin intolerance refers to an inability to use statins because of muscle symptoms
or elevated creatine kinase, and the major diagnostic challenge is to unambiguously link …

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide.
Elevated blood lipids may be a major risk factor for CVD. Due to consistent and robust …

Antecedentes: Por lo general, las estatuias son bien toleradas pero algunos pacientes
suspenden su tratamiento debido a la aparición de efectos adversos. La disponibilidad de …

Statins are effective in reducing cardiovascular events and are safe for almost all patients.
Nevertheless, intolerance to statins is frequently faced in clinical practice. This is mostly due …

Purpose We conducted a meta-analysis of randomized controlled trials (RCTs) and quasi-
RCTs to synthesize evidence about the efficacy and safety of alternate-day vs daily dosing of …

Introduction: Statin intolerance is largely defined by muscle related symptoms, leading to
intolerability and cessation. The nocebo effect coupled with the challenges of diagnosing …