Allogeneic stem cell transplantation for acute myeloid leukemia: who, when, and how?

J Loke, R Buka, C Craddock - Frontiers in immunology, 2021 - frontiersin.org
Although the majority of patients with acute myeloid leukemia (AML) treated with intensive
chemotherapy achieve a complete remission (CR), many are destined to relapse if treated …

Acute graft-versus-host disease of the gut: considerations for the gastroenterologist

S Naymagon, L Naymagon, SY Wong, HM Ko… - Nature Reviews …, 2017 - nature.com
Haematopoietic stem cell transplantation (HSCT) is central to the management of many
haematological disorders. A frequent complication of HSCT is acute graft-versus-host …

Enhanced immunosuppressive properties of human mesenchymal stem cells primed by interferon-γ

DS Kim, IK Jang, MW Lee, YJ Ko, DH Lee, JW Lee… - …, 2018 - thelancet.com
Mesenchymal stem cells (MSCs) are of particular interest for the treatment of immune-
related diseases owing to their immunosuppressive properties. In this study, we aimed to …

Posttransplant cyclophosphamide for prevention of graft-versus-host disease: results of the prospective randomized HOVON-96 trial

AEC Broers, CN de Jong, K Bakunina… - Blood …, 2022 - ashpublications.org
Graft-versus-host disease (GVHD) is the most important complication of allogeneic
hematopoietic stem cell transplantation (alloHSCT). We performed a prospective …

Rabbit ATG/ATLG in preventing graft-versus-host disease after allogeneic stem cell transplantation: consensus-based recommendations by an international expert …

F Bonifazi, MT Rubio, A Bacigalupo… - Bone marrow …, 2020 - nature.com
This collaborative initiative aimed to provide recommendations on the use of polyclonal
antithymocyte globulin (ATG) or anti-T lymphocyte globulin (ATLG) for the prevention of graft …

Acute graft versus host disease: a comprehensive review

S Nassereddine, H Rafei, E Elbahesh… - Anticancer …, 2017 - ar.iiarjournals.org
Acute graft versus host disease (aGVHD) remains the second leading cause of death
following allogeneic hematopoietic stem cell transplant (AHSCT). Over the last five years …

Lessons to learn from low-dose cyclosporin-A: a new approach for unexpected clinical applications

C Flores, G Fouquet, IC Moura, TT Maciel… - Frontiers in …, 2019 - frontiersin.org
Cyclosporin-A has been known and used for a long time, since its “fast track” approval in the
early 80's. This molecule has rapidly demonstrated unexpected immunosuppressive …

[HTML][HTML] Optimizing antithymocyte globulin dosing for unrelated donor allogeneic hematopoietic cell transplantation based on recipient absolute lymphocyte count

VE Kennedy, H Chen, BN Savani, J Greer… - Biology of Blood and …, 2018 - Elsevier
Antithymocyte globulin (ATG) is used as prophylaxis against graft-versus-host disease
(GVHD). Current dosing regimens for ATG are empiric and weight-based, and do not …

Higher cyclosporine-A concentration increases the risk of relapse in AML following allogeneic stem cell transplantation from unrelated donors using anti-thymocyte …

M Lisak, M Nicklasson, R Palmason, S Wichert… - Scientific Reports, 2023 - nature.com
Cyclosporine-A (CsA) is used to prevent acute graft-versus-host disease (aGvHD).
European Society for Blood and Marrow transplantation (EBMT) recommends a CsA target …

Hematopoietic stem cell transplantation activity in Europe

A Gratwohl, H Baldomero… - Current opinion in …, 2013 - journals.lww.com
Hematopoietic stem cell transplantation activity in Europe : Current Opinion in Hematology
Hematopoietic stem cell transplantation activity in Europe : Current Opinion in Hematology Log …