SARS-CoV-2-specific immune response and the pathogenesis of COVID-19

E Gusev, A Sarapultsev, L Solomatina… - International journal of …, 2022 - mdpi.com
The review aims to consolidate research findings on the molecular mechanisms and
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …

[HTML][HTML] Mitochondria-mediated oxidative stress during viral infection

J Foo, G Bellot, S Pervaiz, S Alonso - Trends in Microbiology, 2022 - cell.com
Through oxidative phosphorylation, mitochondria play a central role in energy production
and are an important production source of reactive oxygen species (ROS). Not surprisingly …

Potential and therapeutic roles of diosmin in human diseases

E Huwait, M Mobashir - Biomedicines, 2022 - mdpi.com
Because of their medicinal characteristics, effectiveness, and importance, plant-derived
flavonoids have been a possible subject of research for many years, particularly in the last …

Potential role of antioxidant and anti-inflammatory therapies to prevent severe SARS-Cov-2 complications

AM Fratta Pasini, C Stranieri, L Cominacini, C Mozzini - Antioxidants, 2021 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic is caused by a novel severe acute
respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2). Here, we review the …

The potential role of growth differentiation factor 15 in COVID-19: a corollary subjective effect or not?

AO Babalghith, HM Al-Kuraishy, AI Al-Gareeb… - Diagnostics, 2022 - mdpi.com
Coronavirus disease 2019 (COVID-19) is primarily caused by various forms of severe acute
respiratory syndrome coronavirus type 2 (SARS-CoV-2) variants. COVID-19 is characterized …

A raising dawn of pentoxifylline in management of inflammatory disorders in Covid-19

G Mostafa-Hedeab, HM Al-Kuraishy, AI Al-Gareeb… - …, 2022 - Springer
The existing pandemic viral infection caused by severe acute respiratory syndrome
coronavirus type 2 (SARS-CoV-2) leads to coronavirus disease 2019 (Covid-19). SARS …

Is ferroptosis a key component of the process leading to multiorgan damage in COVID-19?

AM Fratta Pasini, C Stranieri, D Girelli, F Busti… - Antioxidants, 2021 - mdpi.com
Even though COVID-19 is mostly well-known for affecting respiratory pathology, it can also
result in several extrapulmonary manifestations, leading to multiorgan damage. A recent …

Mechanisms contributing to adverse outcomes of COVID-19 in obesity

M Sudhakar, SB Winfred, G Meiyazhagan… - Molecular and cellular …, 2022 - Springer
A growing amount of epidemiological data from multiple countries indicate an increased
prevalence of obesity, more importantly central obesity, among hospitalized subjects with …

Association between vitamin D status and risk of developing severe COVID-19 infection: a meta-analysis of observational studies

M Ben-Eltriki, R Hopefl, JM Wright… - Journal of the American …, 2022 - Taylor & Francis
Objective The relationship between 25-hydroxyvitamin D3 (25 (OH) D), the surrogate marker
for vitamin D3, serum concentration and COVID-19 has come to the forefront as a potential …

Loss of mitochondrial membrane potential (ΔΨm) in leucocytes as post-COVID-19 sequelae

KJG Díaz-Resendiz, AB Benitez-Trinidad… - Journal of Leukocyte …, 2022 - academic.oup.com
The mitochondrial membrane potential (Δ Ψ m) is a parameter often used to determine
mitochondrial function; therefore, it can be used to determine the integrity and functionality of …