MA Schwartz - Trends in cell biology, 2001 - cell.com
Adhesion to the extracellular matrix (ECM) is a crucial regulator of cell function, and it is now well established that signaling by integrins mediates many of these effects. Ten years of …
S Kim, K Iizuka, HSP Kang, A Dokun, AR French… - Nature …, 2002 - nature.com
Natural killer (NK) cells develop in the bone marrow, but their in vivo stages of maturation, expansion and acquisition of receptors that guide target cell specificity are not well defined …
Multicellular organisms must coordinate signals from adhesion receptors with those from other signalling receptors (for example, growth factor receptors). Here, we briefly review …
SC Owen, MS Shoichet - Journal of biomedical materials …, 2010 - Wiley Online Library
A detailed understanding of the biophysical features that affect cell growth and development is important in guiding the design of biomimetic scaffolds. The cellular microenvironment is a …
S Liu, SM Thomas, DG Woodside, DM Rose… - Nature, 1999 - nature.com
The α4 integrins are indispensable for embryogenesis, haematopoiesis and immune responses,, possibly because α4 regulates cellular functions differently from other integrins …
C Ma, Y Rong, DR Radiloff, MB Datto… - Genes & …, 2008 - genesdev.cshlp.org
Metastasis, the major cause of cancer death, is a multistep process that requires interactions between cancer cells and stromal cells and between cancer cells and extracellular matrix …
A Katsumi, T Naoe, T Matsushita, K Kaibuchi… - Journal of Biological …, 2005 - ASBMB
Mechanical tension is a critical determinant of cell growth, differentiation, apoptosis, migration, and development. Integrins have been implicated in sensing force but little is …
JT Pribila, AC Quale, KL Mueller… - Annu. Rev. Immunol …, 2004 - annualreviews.org
Integrin receptors mediate adhesive events that are critical for a specific and effective immune response to foreign pathogens. Integrin-dependent interactions of lymphocytes and …
R Alon, S Feigelson - Seminars in immunology, 2002 - Elsevier
In order to extravasate the bloodstream at specific sites of inflammation or antigen presentation, circulating leukocytes must rapidly translate specific adhesive and stimulatory …