Systemic autoimmune diseases are characterized by the failure of the immune system to
differentiate self from non-self. These conditions are associated with significant morbidity …

Liquid biopsies (LBs), particularly using circulating tumor DNA (ctDNA), are expected to
revolutionize precision oncology and blood-based cancer screening. Recent technological …

Cell-free DNA (cfDNA) fragmentation is nonrandom, at least partially mediated by various
DNA nucleases, forming characteristic cfDNA end motifs. However, there is a paucity of tools …

Plasma cell-free DNA (cfDNA) are small molecules generated through a non-random
fragmentation procedure. Despite commendable translational values in cancer liquid biopsy …

The high fragmentation of nuclear circulating DNA (cirDNA) relies on chromatin organization
and protection or packaging within mononucleosomes, the smallest and the most stabilized …

The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) had spread from
China and, within 2 months, became a global pandemic. The infection from this disease can …

Cell-free DNA molecules are released into the plasma via apoptotic or necrotic events and
active release mechanisms, which carry the genetic and epigenetic information of its origin …

Abstract Background and Purpose Currently there are no widely accepted guidelines for
chimerism analysis testing in hematopoietic cell transplantation (HCT) patients. The …

Cell-free extrachromosomal circular DNA (eccDNA) as a distinct topological form from linear
DNA has recently gained increasing research interest, with possible clinical applications as …

Excessive cell-free DNA (cfDNA) released by damaged or apoptotic cells can cause
inflammation, impacting the progression of rheumatoid arthritis (RA). cfDNA scavengers …