cfGWAS reveal genetic basis of cell-free DNA features

H Zhu, Y Zhang, S Zeng, L Li, R Ou, X Zhang, Y Lin… - medRxiv, 2024 - medrxiv.org
cfDNA consists of degraded DNA fragments released into body fluids. Its genetic and
pathological information makes it useful for prenatal testing and early tumor detection …

The role of DNA in the pathogenesis of SLE: DNA as a molecular chameleon

DS Pisetsky, A Herbert - Annals of the Rheumatic Diseases, 2024 - ard.bmj.com
Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterised by
antibodies to DNA (anti-DNA) and other nuclear macromolecules. Anti-DNA antibodies are …

The Value of Cell-Free Circulating DNA Profiling in Patients with Skin Diseases

J Ma, Y Teng, H Youming, X Tao, Y Fan - Liquid Biopsies: Methods and …, 2023 - Springer
Liquid biopsy, also known as fluid biopsy or fluid-phase biopsy, is the sampling and analysis
of the blood, cerebrospinal fluid, saliva, pleural fluid, ascites, and urine. Compared with …

Nucleic acid liquid biopsies in cardiovascular disease: Cell-free RNA liquid biopsies in cardiovascular disease

S Sharma, T Artner, KT Preissner, IM Lang - Atherosclerosis, 2024 - Elsevier
Cardiovascular diseases (CVD) and their complications continue to be the leading cause of
mortality globally. With recent advancements in molecular analytics, individualized …

Recent advances in liquid biopsy in cancers: Diagnosis, disease state and treatment response monitoring

Z Chen, JWP Yam - Clinical and Translational Discovery, 2022 - Wiley Online Library
Recent years have witnessed the development of scientific research and clinical trials of
liquid biopsy in various diseases, especially cancers. Liquid biopsy refers to a procedure in …

Benefits of applying molecular barcoding systems are not uniform across different genomic applications

J Bieler, S Kubik, M Macheret, C Pozzorini… - Journal of Translational …, 2023 - Springer
Background Despite the wide variety of Next Generation Sequencing (NGS)-based
methods, it remains challenging to detect mutations present at very low frequencies. This …

In Vitro Analysis of Biological Activity of Circulating Cell-Free DNA Isolated from Blood Plasma of Schizophrenic Patients and Healthy Controls—Part 2: Adaptive …

SV Kostyuk, ES Ershova, AV Martynov, AV Artyushin… - Genes, 2022 - mdpi.com
Oxidized in vitro genomic DNA (gDNA) is known to launch an adaptive response in human
cell cultures. The cfDNA extracted from the plasma of schizophrenic patients (sz-cfDNA) and …

Recombinant Deoxyribonuclease I eye Drops for ocular graft versus host disease: Results of a randomized clinical trial

CS Mun, B Surenkhuu, YF Chen, N Atassi… - Eye & Contact …, 2022 - journals.lww.com
Objective: We have previously shown that neutrophil extracellular traps (NETs) are present
on the ocular surface of patients with ocular graft versus host disease (oGVHD), contributing …

Characterization of Serous Cell-Free DNA in Myelodysplastic Syndromes

H Zhu, G Feng, N Zhao, L Wu, Z Long - Cell Transplantation, 2022 - journals.sagepub.com
Myelodysplastic syndromes (MDS) are a group of malignant clonal diseases presenting
abnormal development of acquired hematopoietic progenitor/stem cell myeloid …

Applying Genomics to Unravel Health Disparities in Organ Transplantation: Paul I. Terasaki State-of-the-art Lecture; American Transplant Congress 2021

HA Valantine - Transplantation, 2023 - journals.lww.com
An extensive body of research about team science provides empirical evidence that diverse
teams outperform homogenous teams in creating more innovative solutions to complex …