Male infertility is a multifactorial complex disease with highly heterogeneous phenotypic
representation and in at least 15% of cases, this condition is related to known genetic …

During implantation, a symphony of interaction between the trophoblast originated from the
trophectoderm of the implanting blastocyst and the endometrium leads to a successful …

• In this guideline, recurrent miscarriage has been defined as three or more first trimester
miscarriages. However, clinicians are encouraged to use their clinical discretion to …

Anti-inflammatory Th2 cytokines have been shown to be associated with healthy, successful
pregnancy while pro-inflammatory Th1 and Th17 cytokines are associated with pregnancy …

The roles of genetic polymorphisms in the pathogenesis of recurrent miscarriage (RM) have
been intensively studied. However, the results of these studies were inconsistent, especially …

There is a trend towards offering immunotherapy to women with unexplained reproductive
failure based on abnormal Natural Killer (NK) cell levels. Previous systematic reviews …

Purpose Numerous studies have investigated the associations between
methylenetetrahydrofolate reductase (MTHFR) gene C677T and A1298C polymorphisms …

Background Thrombophilia is reported to be a candidate etiology of recurrent pregnancy
loss (RPL). No conclusive results on the association between prothrombin G20210A …

This article discusses the current trends in the diagnosis and treatment of recurrent
pregnancy loss. Genetic testing of the miscarriage tissue by 23-chromosome microarray and …

Recurrent pregnancy loss (RPL) is a common reproductive problem affecting around 5% of
couples worldwide. At present, about half of RPL cases remained unexplained. Previous …