[HTML][HTML] The importance of measuring SARS-CoV-2-specific T-cell responses in an ongoing pandemic

L Petrone, A Sette, RD de Vries, D Goletti - Pathogens, 2023 - mdpi.com
Neutralizing antibodies are considered a correlate of protection against SARS-CoV-2
infection and severe COVID-19, although they are not the only contributing factor to …

[HTML][HTML] Global landscape of COVID-19 research: a visualization analysis of randomized clinical trials

SH Zyoud - Clinical and Experimental Medicine, 2024 - Springer
The emergence of COVID-19 in 2019 has resulted in a significant global health crisis.
Consequently, extensive research was published to understand and mitigate the disease. In …

[HTML][HTML] SARS-CoV-2 breakthrough infections according to the immune response elicited after mRNA third dose vaccination in COVID-19-Naïve Hospital Personnel

A Santoro, A Capri, D Petrone, F Colavita, S Meschi… - Biomedicines, 2023 - mdpi.com
Background: Vaccine-induced SARS-CoV-2-anti-spike antibody (anti-S/RBD) titers are often
used as a marker of immune protection and to anticipate the risk of breakthrough infections …

[HTML][HTML] Dynamic evolution of humoral and T-cell specific immune response to COVID-19 mRNA vaccine in patients with multiple sclerosis followed until the booster …

S Ruggieri, A Aiello, C Tortorella, A Navarra… - International Journal of …, 2023 - mdpi.com
This study characterizes antibody and T-cell immune responses over time until the booster
dose of COronaVIrus Disease 2019 (COVID-19) vaccines in patients with multiple sclerosis …

Protein–protein interactions in solutions of monoclonal antibodies probed by the dependence of the high-frequency viscosity on temperature and concentration

E Rott, C Leppin, T Diederichs, P Garidel… - Analyst, 2023 - pubs.rsc.org
Using a quartz crystal microbalance with dissipation monitoring (QCM-D), the complex high-
frequency viscosity,= η′− iη′′, of concentrated solutions of a monoclonal antibody (mAb) …

[HTML][HTML] Editorial for the Topical Collection “SARS-CoV-2 Infection and COVID-19 Disease”

L Martinez-Sobrido, ML DeDiego - Pathogens, 2024 - mdpi.com
A previously unknown coronavirus, named Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2), emerged in the city of Wuhan, China, in December 2019. Its …

[HTML][HTML] Antiviral and Monoclonal Antibody Combination Therapy in Haematological Patients in the Omicron Era

S Vita, E Giombini, P De Marco, M Rueca… - … of Hematology and …, 2024 - ncbi.nlm.nih.gov
Immunocompromised (IC) patients are at higher risk for persistent and/or severe SARS-CoV-
2 infection caused by different viral variants, with a high casefatality ratio. 1, 2 The first …

[HTML][HTML] Prolonged SARS-CoV-2 Infection in Patients Receiving Anti-CD20 Monoclonal Antibodies: A Diagnostic Challenged by Negative Nasopharyngeal RT-PCR …

L Da Silva, T Klopfenstein, V Gendrin, J Clouet, L Toko… - Viruses, 2023 - mdpi.com
We highlighted in this current paper similar prolonged respiratory presentation with COVID-
19 pneumonia in four severely immunocompromised patients currently being treated with …

Host-directed therapies: old and new approaches for the treatment of infections

D Goletti, CWM Ong, JS Friedland - International Journal of Infectious …, 2024 - ijidonline.com
In the last 20 years, zoonotic diseases have been responsible for important outbreaks such
as Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome …

[HTML][HTML] Managing COVID-19 in children

J Vosu - Medicine Today, 2023 - medicinetoday.com.au
Abstract SARS-CoV-2 infection, which can lead to severe disease known as COVID-19,
differs in children compared with adults. The differences are not only in the clinical …