[HTML][HTML] Application of pseudovirus system in the development of vaccine, antiviral-drugs, and neutralizing antibodies
Q Xiang, L Li, J Wu, M Tian, Y Fu - Microbiological Research, 2022 - Elsevier
Pseudoviruses are viral particles coated with a heterologous envelope protein, which
mediates the entry of pseudoviruses as efficiently as that of the live viruses possessing high …
mediates the entry of pseudoviruses as efficiently as that of the live viruses possessing high …
Rapid assessment of SARS-CoV-2–evolved variants using virus-like particles
Efforts to determine why new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) variants demonstrate improved fitness have been limited to analyzing mutations in the …
2) variants demonstrate improved fitness have been limited to analyzing mutations in the …
Potential for early noninvasive COVID-19 detection using electronic-nose technologies and disease-specific VOC metabolic biomarkers
AD Wilson, LB Forse - Sensors, 2023 - mdpi.com
The established efficacy of electronic volatile organic compound (VOC) detection
technologies as diagnostic tools for noninvasive early detection of COVID-19 and related …
technologies as diagnostic tools for noninvasive early detection of COVID-19 and related …
[HTML][HTML] In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the ongoing
coronavirus disease 2019 (COVID-19) pandemic. Understanding of the RNA virus and its …
coronavirus disease 2019 (COVID-19) pandemic. Understanding of the RNA virus and its …
SARS‐CoV‐2 ORF10 antagonizes STING‐dependent interferon activation and autophagy
L Han, Y Zheng, J Deng, ML Nan, Y Xiao… - Journal of medical …, 2022 - Wiley Online Library
A characteristic feature of COVID‐19, the disease caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2) infection, is the dysregulated immune response …
syndrome coronavirus 2 (SARS‐CoV‐2) infection, is the dysregulated immune response …
Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron BA. 1 variant through NSP6
Abstract Although the SARS-CoV-2 Omicron variant (BA. 1) spread rapidly across the world
and effectively evaded immune responses, its viral fitness in cell and animal models was …
and effectively evaded immune responses, its viral fitness in cell and animal models was …
A live-attenuated SARS-CoV-2 vaccine candidate with accessory protein deletions
We report a live-attenuated SARS-CoV-2 vaccine candidate with (i) re-engineered viral
transcription regulator sequences and (ii) deleted open-reading-frames (ORF) 3, 6, 7, and 8 …
transcription regulator sequences and (ii) deleted open-reading-frames (ORF) 3, 6, 7, and 8 …
Replication and single-cycle delivery of SARS-CoV-2 replicons
Molecular virology tools are critical for basic studies of the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) and for developing new therapeutics. Experimental …
syndrome coronavirus 2 (SARS-CoV-2) and for developing new therapeutics. Experimental …
Comparison of viral RNA–host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2
In contrast to the extensive research about viral protein–host protein interactions that has
revealed major insights about how RNA viruses engage with host cells during infection, few …
revealed major insights about how RNA viruses engage with host cells during infection, few …
SARS-CoV-2 nucleocapsid protein phase separates with G3BPs to disassemble stress granules and facilitate viral production
A key to tackling the coronavirus disease 2019 (COVID-19) pandemic is to understand how
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) manages to outsmart host …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) manages to outsmart host …