Microcrystal electron diffraction (MicroED) allows for macromolecular structure solution from
nanocrystals. To create crystals of suitable size for MicroED data collection, sample …

Recent technical advances have dramatically increased the power and scope of structural
biology. New developments in high-resolution cryo-electron microscopy, serial X-ray …

Microcrystal electron diffraction (MicroED) combines crystallography and electron cryo-
microscopy (cryo-EM) into a method that is applicable to high-resolution structure …

One of the key goals in single-particle cryo-microscopy is to obtain a uniform distribution of
particle orientations, so that the three-dimensional structure has isotropic resolution in …

Along with the adoption of three-dimensional electron diffraction (3D ED/MicroED) as a
mainstream tool for structure determination from sub-micron single crystals, questions about …

Innovative new crystallographic methods are facilitating structural studies from ever smaller
crystals of biological macromolecules. In particular, serial X-ray crystallography and …

A structure of the murine voltage-dependent anion channel (VDAC) was determined by
microcrystal electron diffraction (MicroED). Microcrystals of an essential mutant of VDAC …

The advancement of single-crystal structural analysis has emerged as a pivotal technology
surpassing spectroscopic methods in revealing the intricate structural details of organic …

Microcrystal electron diffraction, or MicroED, is a method that is capable of determining
structure from very small and thin 3D crystals using a transmission electron microscope …

Traditionally, molecular assembly pathways for viruses are inferred from high resolution
structures of purified stable intermediates, low resolution images of cell sections and genetic …