The cellular response to genotoxic stress is mediated by a well-characterized network of
DNA surveillance pathways. The contribution of post-transcriptional gene regulatory …

Studies have found that RNA encoding proteins only account for a small part of the total
number, most RNA is non-coding RNA, and non-coding RNA may affect the occurrence and …

Neurodegenerative diseases (NDDs) have become a significant global public health
problem and a major societal burden. The World Health Organization predicts that NDDs will …

Obesity, a major global health issue, is increasingly associated with the integral role of long
non-coding RNA (lncRNA) in adipogenesis. Recently, we found that lncRNA-MSTRG4710 …

Gene expression programs change during cellular transitions. It is well established that a
network of transcription factors and chromatin modifiers regulate RNA levels during …

Most of the eukaryotic genome is pervasively transcribed, yielding hundreds to thousands of
long noncoding RNAs (lncRNAs) and circular RNAs (circRNAs), some of which are well …

Recent reports show that long non-coding RNAs (lncRNAs) have inefficient splicing and
fewer alternative splice variants than mRNAs. Here, we have explored the efficiency of …

Chronic obstructive pulmonary disease (COPD) is characterized by progressive and
irreversible airflow obstruction with abnormal lung function. Because its pathogenesis …

The majority of transcriptionally active RNA derived from the mammalian genome does not
code for protein. Long noncoding RNA (lncRNA) is the most abundant form of noncoding …

Transcription is common at active mammalian enhancers sometimes giving rise to stable
enhancer-associated long intergenic noncoding RNAs (elincRNAs). Expression of elincRNA …