Long non-coding RNAs (lncRNAs) are rapidly emerging as important regulators of a diverse
array of cellular functions. Here, we describe a meta-analysis of two independent RNA-seq …

CLIP-seq methods allow the generation of genome-wide maps of RNA binding protein–RNA
interaction sites. However, due to differences between different CLIP-seq assays, existing …

Alzheimer's disease (AD) is the most common type of dementia, but its pathogenesis is not
fully understood, and effective drugs to treat or reverse the progression of the disease are …

Most mammalian genes have multiple polyA sites, representing a substantial source of
transcript diversity regulated by the cleavage and polyadenylation (CPA) machinery. To …

Background Studies have revealed the aberrant expression of lncRNAs is responsible for
human carcinogenesis. MIR4697 host gene (MIR4697HG) is an upregulated lncRNA that …

Long non-coding RNAs (lncRNAs) have emerged as fundamental regulators in various
biological processes, including embryonic development and cellular differentiation. Despite …

Adrenal steroid hormone production is a dynamic process stimulated by adrenocorticotropic
hormone (ACTH) and angiotensin II (AngII). These ligands initialize a rapid and robust gene …

In this review I focus on the role of splicing in long non-coding RNA (lncRNA) life. First, I
summarize differences between the splicing efficiency of protein-coding genes and lncRNAs …

The evolutionary conserved Taurine Upregulated Gene 1 (TUG1) is a ubiquitously
expressed gene that is one of the highest expressed genes in human and rodent endothelial …

The level of each RNA species depends on the balance between its rates of production and
decay. Although previous studies have measured RNA decay across the genome in tissue …