[HTML][HTML] Global scientific trends on the immunomodulation of mesenchymal stem cells in the 21st century: A bibliometric and visualized analysis

Z Wang, Y Sun, R Shen, X Tang, Y Xu… - Frontiers in …, 2022 - frontiersin.org
Background Since the discovery of the immunomodulatory functions of mesenchymal stem
cells (MSCs), their application in immunomodulation has attracted considerable attention …

Establishing an hTERT-driven immortalized umbilical cord-derived mesenchymal stem cell line and its therapeutic application in mice with liver failure

Q Chen, M Jin, S Wang, K Wang… - Journal of Tissue …, 2023 - journals.sagepub.com
Acute liver failure (ALF) is characterized by rapid liver cell destruction. It is a multi-etiological
and fulminant complication with a clinical mortality of over 80%. Therapy using …

Engineering of immune microenvironment for enhanced tissue remodeling

GR Ko, JS Lee - Tissue Engineering and Regenerative Medicine, 2022 - Springer
The capability to restore the structure and function of tissues damaged by fatal diseases and
trauma is essential for living organisms. Various tissue engineering approaches have been …

[HTML][HTML] Mesenchymal stem cells: emerging concepts and recent advances in their roles in organismal homeostasis and therapy

P Liu, Y An, T Zhu, S Tang, X Huang, S Li… - Frontiers in Cellular …, 2023 - frontiersin.org
Stem cells play a crucial role in re-establishing homeostasis in the body, and the search for
mechanisms by which they interact with the host to exert their therapeutic effects remains …

Topical administration of the secretome derived from human amniotic epithelial cells ameliorates psoriasis-like skin lesions in mice

M Yang, L Wang, Z Chen, W Hao, Q You, J Lin… - Stem Cell Research & …, 2022 - Springer
Background Psoriasis is a chronic inflammatory skin disease. Tissue stem cells have
exhibited a therapeutic effect on psoriatic mice. However, the therapeutic effect of topical …

Musculoskeletal Organs‐on‐Chips: An Emerging Platform for Studying the Nanotechnology–Biology Interface

Y Wang, P Yung, G Lu, Y Liu, C Ding, C Mao… - Advanced …, 2024 - Wiley Online Library
Nanotechnology‐based approaches are promising for the treatment of musculoskeletal
(MSK) disorders, which present significant clinical burdens and challenges, but their clinical …

Umbilical cord mesenchymal stromal cells for steroid-refractory acute graft-versus-host disease

CD Donadel, BG Pires, NC André, TCM Costa… - Pharmaceuticals, 2023 - mdpi.com
Background: Steroid-refractory acute graft-vs.-host disease (SR-aGVHD) is a complication of
allogeneic hematopoietic stem cell transplantation with a dismal prognosis and for which …

hMSCs treatment attenuates murine herpesvirus-68 (MHV-68) pneumonia through altering innate immune response via ROS/NLRP3 signaling pathway

A Qin, X Wang, J Fu, A Shen, X Huang, Z Chen… - Molecular …, 2023 - Springer
Immunocompromised individuals are particularly vulnerable to viral infections and
reactivation, especially endogenous herpes viruses such as Epstein-Barr virus (EBV), a …

[HTML][HTML] Human mesenchymal stem cells exhibit altered mitochondrial dynamics and poor survival in high glucose microenvironment

E Abu-El-Rub, F Almahasneh… - World Journal of Stem …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Mesenchymal stem cells (MSCs) are a type of stem cells that possess
relevant regenerative abilities and can be used to treat many chronic diseases. Diabetes …

All-trans retinoic acid inhibits the osteogenesis of periodontal ligament stem cells by promoting IL-1β production via NF-κB signaling

L Guo, Y Zhang, H Liu, Q Cheng, S Yang… - International …, 2022 - Elsevier
All-trans retinoic acid (ATRA), a main derivative of vitamin A, has been shown to affect the
osteogenic differentiation of mesenchymal stem cells (MSCs). Periodontal ligament stem …