Update on extracellular vesicle-based vaccines and therapeutics to combat COVID-19
T Mustajab, MS Kwamboka, DA Choi, DW Kang… - International Journal of …, 2022 - mdpi.com
The COVID-19 pandemic has had a deep impact on people worldwide since late 2019 when
SARS-CoV-2 was first identified in Wuhan, China. In addition to its effect on public health, it …
SARS-CoV-2 was first identified in Wuhan, China. In addition to its effect on public health, it …
Assessing Extracellular Vesicles in Human Biofluids Using Flow‐Based Analyzers
KHW Yim, O Krzyzaniak, A Al Hrout… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are increasingly being analyzed by flow cytometry. Yet their
minuscule size and low refractive index cause the scatter intensity of most EVs to fall below …
minuscule size and low refractive index cause the scatter intensity of most EVs to fall below …
Extensive blood transcriptome analysis reveals cellular signaling networks activated by circulating glycocalyx components reflecting vascular injury in COVID-19
M Borrmann, F Brandes, B Kirchner, M Klein… - Frontiers in …, 2023 - frontiersin.org
Background Degradation of the endothelial protective glycocalyx layer during COVID-19
infection leads to shedding of major glycocalyx components. These circulating proteins and …
infection leads to shedding of major glycocalyx components. These circulating proteins and …
CD66b+/CD68+ circulating extracellular vesicles, lactate dehydrogenase and neutrophil‐to‐lymphocyte ratio can differentiate coronavirus disease 2019 severity …
Abstract Coronavirus disease 2019 (COVID‐19) has been a major public health burden. We
hypothesised that circulating extracellular vesicles (cEVs), key players in health and …
hypothesised that circulating extracellular vesicles (cEVs), key players in health and …
Investigating the tumor-immune microenvironment through extracellular vesicles from frozen patient biopsies and 3D cultures
A Al Hrout, MP Levesque, R Chahwan - Frontiers in Immunology, 2023 - frontiersin.org
Melanomas are highly immunogenic tumors that have been shown to activate the immune
response. Nonetheless, a significant portion of melanoma cases are either unresponsive to …
response. Nonetheless, a significant portion of melanoma cases are either unresponsive to …
[HTML][HTML] Metabolic modeling elucidates phenformin and atpenin A5 as broad-spectrum antiviral drugs
A Renz, M Hohner, M Breitenbach… - 2022 - europepmc.org
The SARS-CoV-2 pandemic has reemphasized the urgent need to develop broad-spectrum
antiviral therapies. We developed a computational pipeline that uses scRNA-Seq data to …
antiviral therapies. We developed a computational pipeline that uses scRNA-Seq data to …
Feline coronavirus influences the biogenesis and composition of extracellular vesicles derived from CRFK cells
SVT Wijerathne, R Pandit, AO Ipinmoroti… - Frontiers in Veterinary …, 2024 - frontiersin.org
Introduction Coronavirus (CoV) has become a public health crisis that causes numerous
illnesses in humans and certain animals. Studies have identified the small, lipid-bound …
illnesses in humans and certain animals. Studies have identified the small, lipid-bound …
Extracellular vesicle features are associated with COVID‐19 severity
F Caponnetto, M De Martino… - Journal of Cellular …, 2023 - Wiley Online Library
Abstract COVID‐19 is heterogeneous; therefore, it is crucial to identify early biomarkers for
adverse outcomes. Extracellular vesicles (EV) are involved in the pathophysiology of COVID …
adverse outcomes. Extracellular vesicles (EV) are involved in the pathophysiology of COVID …
[HTML][HTML] Exploring extracellular vesicles as mediators of clinical disease and vehicles for viral therapeutics: Insights from the COVID-19 pandemic
VD Craddock, CM Cook, NK Dhillon - Extracellular vesicles and …, 2022 - ncbi.nlm.nih.gov
The COVID-19 pandemic has challenged researchers to rapidly understand the capabilities
of the SARS-CoV-2 virus and investigate potential therapeutics for SARS-CoV-2 infection …
of the SARS-CoV-2 virus and investigate potential therapeutics for SARS-CoV-2 infection …