Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth

X Wang, S Tang, SY Le, R Lu, JS Rader, C Meyers… - PloS one, 2008 - journals.plos.org
MicroRNAs (miRNAs) play important roles in cancer development. By cloning and
sequencing of a HPV16+ CaSki cell small RNA library, we isolated 174 miRNAs (including …

[HTML][HTML] Virus-encoded microRNAs

A Grundhoff, CS Sullivan - Virology, 2011 - Elsevier
MicroRNAs (miRNAs) are the subject of enormous interest. They are small non-coding
RNAs that play a regulatory role in numerous and diverse cellular processes such as …

Circular DNA tumor viruses make circular RNAs

T Toptan, B Abere, MA Nalesnik… - Proceedings of the …, 2018 - National Acad Sciences
Epstein− Barr virus (EBV) and Kaposi's sarcoma herpesvirus (KSHV) cause∼ 2% of all
human cancers. RNase R-resistant RNA sequencing revealed that both …

Reactivation and lytic replication of Kaposi's sarcoma-associated herpesvirus: an update

KK Aneja, Y Yuan - Frontiers in microbiology, 2017 - frontiersin.org
The life cycle of Kaposi's sarcoma-associated herpesvirus (KSHV) consists of two phases,
latent and lytic. The virus establishes latency as a strategy for avoiding host immune …

Kaposi sarcoma–associated herpesvirus: immunobiology, oncogenesis, and therapy

DP Dittmer, B Damania - The Journal of clinical …, 2016 - Am Soc Clin Investig
Kaposi sarcoma–associated herpesvirus (KSHV), also known as human herpesvirus 8, is
the etiologic agent underlying Kaposi sarcoma, primary effusion lymphoma, and multicentric …

[HTML][HTML] Diverse herpesvirus microRNAs target the stress-induced immune ligand MICB to escape recognition by natural killer cells

D Nachmani, N Stern-Ginossar, R Sarid… - Cell host & …, 2009 - cell.com
Herpesviruses are known for their persistent lifelong latent infection, which is made possible
by their vast repertoire of immune-evasion strategies. We have previously shown that a …

KSHV and the pathogenesis of Kaposi sarcoma: listening to human biology and medicine

D Ganem - The Journal of clinical investigation, 2010 - Am Soc Clin Investig
The linkage of Kaposi sarcoma (KS) to infection by a novel human herpesvirus (Kaposi
sarcoma–associated herpesvirus [KSHV]) is one of the great successes of contemporary …

Epstein–Barr virus microRNAs are evolutionarily conserved and differentially expressed

X Cai, A Schäfer, S Lu, JP Bilello, RC Desrosiers… - PLoS …, 2006 - journals.plos.org
The pathogenic lymphocryptovirus Epstein–Barr virus (EBV) is shown to express at least 17
distinct microRNAs (miRNAs) in latently infected cells. These are arranged in two clusters …

Viral latency and its regulation: lessons from the γ-herpesviruses

SH Speck, D Ganem - Cell host & microbe, 2010 - cell.com
Latency is a state of cryptic viral infection associated with genomic persistence and highly
restricted gene expression. Its hallmark is reversibility: under appropriate circumstances …

MicroRNAs in disease and potential therapeutic applications

HS Soifer, JJ Rossi, P Sætrom - Molecular therapy, 2007 - cell.com
MicroRNAs (miRNAs) are 21–24 nucleotide (nt) duplex RNAs that are created from
precursor transcripts by subsequent processing steps mediated by members of the RNAseIII …