Viral and cellular microRNAs as determinants of viral pathogenesis and immunity

E Gottwein, BR Cullen - Cell host & microbe, 2008 - cell.com
MicroRNAs (miRNAs) have recently emerged as key posttranscriptional regulators of gene
expression in multicellular eukaryotes. It is increasingly clear that miRNAs of both viral and …

Cellular cofactors affecting hepatitis C virus infection and replication

G Randall, M Panis, JD Cooper… - Proceedings of the …, 2007 - National Acad Sciences
Recently identified hepatitis C virus (HCV) isolates that are infectious in cell culture provide
a genetic system to evaluate the significance of virus–host interactions for HCV replication …

The role of RNAi and microRNAs in animal virus replication and antiviral immunity

JL Umbach, BR Cullen - Genes & development, 2009 - genesdev.cshlp.org
The closely related microRNA (miRNA) and RNAi pathways have emerged as important
regulators of virus–host cell interactions. Although both pathways are relatively well …

HIV-associated lymphomas and gamma-herpesviruses

A Carbone, E Cesarman, M Spina… - Blood, The Journal …, 2009 - ashpublications.org
Among the most common HIV-associated lymphomas are Burkitt lymphoma (BL) and diffuse
large B-cell lymphoma (DLBCL) with immunoblastic-plasmacytoid differentiation (also …

A combined computational and microarray-based approach identifies novel microRNAs encoded by human gamma-herpesviruses

A Grundhoff, CS Sullivan, D Ganem - Rna, 2006 - rnajournal.cshlp.org
We have developed an approach to identify microRNAs (miRNAs) that is based on
bioinformatics and array-based technologies, without the use of cDNA cloning. The …

Viruses and microRNAs

BR Cullen - Nature genetics, 2006 - nature.com
The discovery of RNA interference and cellular microRNAs (miRNAs) has not only affected
how biological research is conducted but also revealed an entirely new level of post …

Kaposi's sarcoma-associated herpesvirus encodes an ortholog of miR-155

RL Skalsky, MA Samols, KB Plaisance, IW Boss… - Journal of …, 2007 - Am Soc Microbiol
MicroRNAs (miRNAs) are small noncoding RNAs that posttranscriptionally regulate gene
expression by binding to 3′-untranslated regions (3′ UTRs) of target mRNAs. Kaposi's …

Cohesins localize with CTCF at the KSHV latency control region and at cellular c‐myc and H19/Igf2 insulators

W Stedman, H Kang, S Lin, JL Kissil… - The EMBO …, 2008 - embopress.org
Cohesins, which mediate sister chromatin cohesion, and CTCF, which functions at
chromatin boundaries, play key roles in the structural and functional organization of …

Gammaherpesviruses and lymphoproliferative disorders

E Cesarman - Annual Review of Pathology: Mechanisms of …, 2014 - annualreviews.org
Epstein–Barr virus (EBV) and Kaposi's sarcoma herpesvirus (KSHV), formally designated
human herpesvirus 4 (HHV-4) and 8 (HHV-8), respectively, are viruses that can cause a …

The role of microRNAs in the pathogenesis of herpesvirus infection

D Piedade, JM Azevedo-Pereira - Viruses, 2016 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs important in gene regulation. They are
able to regulate mRNA translation through base-pair complementarity. Cellular miRNAs …