Kaposi sarcoma-associated herpesvirus (KSHV) is a double-stranded DNA herpesvirus
belonging to the γ-herpesvirinae subfamily. KSHV has been associated with the …

Kaposi's sarcoma-associated herpesvirus (KSHV) is causally linked to several acquired
immune deficiency syndrome-related malignancies, including Kaposi's sarcoma, primary …

Herpesvirus latency is generally thought to be governed by epigenetic modifications, but the
dynamics of viral chromatin at early timepoints of latent infection are poorly understood …

MicroRNAs (miRNA) play pivotal roles in controlling cell proliferation and differentiation.
Aberrant miRNA expression in human is becoming recognized as a new molecular …

Kaposi sarcoma associated herpesvirus (KSHV), a γ2-herpesvirus, also known as human
herpesvirus-8, is the etiologic agent of three virally associated tumors: Kaposi sarcoma, a …

MicroRNAs (miRNAs) are 19 to 23 nucleotide–long RNAs that post-transcriptionally regulate
gene expression. Human cells express several hundred miRNAs which regulate important …

Although multiple studies have documented the expression of over 70 novel virus-encoded
microRNAs (miRNAs), the targets and functions of most of these regulatory RNA species are …

Adoptive T-cell therapy using lymphocytes genetically engineered to express tumor antigen-
specific TCRs is an attractive strategy for treating patients with malignancies. However, there …

A quantitative algorithm was developed and applied to predict target genes of microRNAs
encoded by herpesviruses. Although there is almost no conservation among microRNAs of …

Herpesviruses encode numerous microRNAs (miRNAs), most of whose functions are
unknown. The Kaposi's sarcoma-associated herpesvirus (KSHV) encodes 17 known …