The mRNA targets of microRNAs (miRNAs) can be identified by immunoprecipitation of Argonaute (Ago) protein-containing RNA-induced silencing complexes (RISCs) followed by …
L Giffin, B Damania - Advances in virus research, 2014 - Elsevier
Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8) is the etiologic agent of Kaposi's sarcoma, primary effusion lymphoma, and multicentric …
Analyses of small RNA expression profiles have revealed that several DNA viruses— including particularly, herpesviruses—express high levels of multiple viral microRNAs …
C Cui, A Griffiths, G Li, LM Silva, MF Kramer… - Journal of …, 2006 - Am Soc Microbiol
MicroRNAs (miRNAs) are key regulators of gene expression in higher eukaryotes. Recently, miRNAs have been identified from viruses with double-stranded DNA genomes. To attempt …
Two lymphotropic human gamma herpesviruses can cause lymphoproliferative disorders: Epstein Barr virus (EBV, formally designated as human herpesvirus 4) and Kaposi sarcoma …
CC Esau, BP Monia - Advanced drug delivery reviews, 2007 - Elsevier
MiRNAs are a conserved class of non-coding RNAs that negatively regulate gene expression post-transcriptionally. Although their biological roles are largely unknown …
I Haecker, LA Gay, Y Yang, J Hu, AM Morse… - 2012 - journals.plos.org
KSHV is the etiological agent of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and a subset of multicentricCastleman's disease (MCD). The fact that KSHV-encoded …
J Burnside, E Bernberg, A Anderson, C Lu… - Journal of …, 2006 - Am Soc Microbiol
MicroRNAs (miRNAs) are a class of small (∼ 22-nucleotide) regulatory molecules that block translation or induce degradation of target mRNAs. These have been identified in a wide …
F Lu, W Stedman, M Yousef, R Renne… - Journal of …, 2010 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV) encodes a cluster of 12 microRNAs (miRNAs) that are processed from a transcript that is embedded within the major latency …