Cellular versus viral microRNAs in host–virus interaction
MicroRNAs (miRNAs) mark a new paradigm of RNA-directed gene expression regulation in
a wide spectrum of biological systems. These small non-coding RNAs can contribute to the …
a wide spectrum of biological systems. These small non-coding RNAs can contribute to the …
Tandem array–based expression screens identify host mRNA targets of virus-encoded microRNAs
JM Ziegelbauer, CS Sullivan, D Ganem - Nature genetics, 2009 - nature.com
MicroRNAs (miRNAs) are short noncoding RNAs of cellular and viral origin,,,,, that post-
transcriptionally regulate gene expression through imperfect base pairing to their mRNA …
transcriptionally regulate gene expression through imperfect base pairing to their mRNA …
Mechanisms of Kaposi′ s sarcoma‐associated herpesvirus latency and reactivation
F Ye, X Lei, SJ Gao - Advances in virology, 2011 - Wiley Online Library
The life cycle of Kaposi′ s sarcoma‐associated herpesvirus (KSHV) consists of latent and
lytic replication phases. During latent infection, only a limited number of KSHV genes are …
lytic replication phases. During latent infection, only a limited number of KSHV genes are …
KSHV-encoded miRNAs target MAF to induce endothelial cell reprogramming
A Hansen, S Henderson, D Lagos… - Genes & …, 2010 - genesdev.cshlp.org
Kaposi sarcoma herpesvirus (KSHV) induces transcriptional reprogramming of endothelial
cells. In particular, KSHV-infected lymphatic endothelial cells (LECs) show an up-regulation …
cells. In particular, KSHV-infected lymphatic endothelial cells (LECs) show an up-regulation …
MicroRNA: an emerging therapeutic target and intervention tool
Z Liu, A Sall, D Yang - International journal of molecular sciences, 2008 - mdpi.com
MicroRNAs (miRNAs) are a class of short non-coding RNAs with posttranscriptional
regulatory functions. To date, more than 600 human miRNAs have been experimentally …
regulatory functions. To date, more than 600 human miRNAs have been experimentally …
A human herpesvirus microRNA inhibits p21 expression and attenuates p21-mediated cell cycle arrest
E Gottwein, BR Cullen - Journal of virology, 2010 - Am Soc Microbiol
The oncogenic human gammaherpesvirus Kaposi's sarcoma-associated herpesvirus
(KSHV) expresses 12 viral microRNAs (miRNAs) in latently infected cells. Here, we report …
(KSHV) expresses 12 viral microRNAs (miRNAs) in latently infected cells. Here, we report …
Towards an understanding of the herpes simplex virus type 1 latency‐reactivation cycle
GC Perng, C Jones - Interdisciplinary perspectives on infectious …, 2010 - Wiley Online Library
Infection by herpes simplex virus type 1 (HSV‐1) can cause clinical symptoms in the
peripheral and central nervous system. Recurrent ocular shedding can lead to corneal …
peripheral and central nervous system. Recurrent ocular shedding can lead to corneal …
Human cytomegalovirus infection alters the expression of cellular microRNA species that affect its replication
The human genome encodes over 500 microRNAs (miRNAs), small RNAs (19 to 26
nucleotides [nt]) that regulate the expressions of diverse cellular genes. Many cellular …
nucleotides [nt]) that regulate the expressions of diverse cellular genes. Many cellular …
Herpesviral latency—common themes
M Weidner-Glunde, E Kruminis-Kaszkiel… - Pathogens, 2020 - mdpi.com
Latency establishment is the hallmark feature of herpesviruses, a group of viruses, of which
nine are known to infect humans. They have co-evolved alongside their hosts, and mastered …
nine are known to infect humans. They have co-evolved alongside their hosts, and mastered …
Kaposi's sarcoma herpesvirus microRNAs induce metabolic transformation of infected cells
O Yogev, D Lagos, T Enver, C Boshoff - PLoS pathogens, 2014 - journals.plos.org
Altered cell metabolism is inherently connected with pathological conditions including
cancer and viral infections. Kaposi's sarcoma-associated herpesvirus (KSHV) is the …
cancer and viral infections. Kaposi's sarcoma-associated herpesvirus (KSHV) is the …