Immune evasion by Kaposi's sarcoma-associated herpesvirus

L Coscoy - Nature Reviews Immunology, 2007 - nature.com
To efficiently establish a persistent infection, Kaposi's sarcoma-associated herpesvirus
(KSHV; also known as HHV8) dedicates a large amount of its coding potential to produce …

A novel assay for viral microRNA function identifies a single nucleotide polymorphism that affects Drosha processing

E Gottwein, X Cai, BR Cullen - Journal of virology, 2006 - Am Soc Microbiol
MicroRNAs (miRNAs) are a class of∼ 22-nucleotide noncoding RNAs that inhibit the
expression of specific target genes at the posttranscriptional level. Recently, 11 miRNAs …

Long-term-infected telomerase-immortalized endothelial cells: a model for Kaposi's sarcoma-associated herpesvirus latency in vitro and in vivo

FQ An, HM Folarin, N Compitello, J Roth… - Journal of …, 2006 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV) is associated with Kaposi's sarcoma (KS),
primary effusion lymphoma (PEL), and multicentric Castleman's disease. Most KS tumor …

Array-based transcript profiling and limiting-dilution reverse transcription-PCR analysis identify additional latent genes in Kaposi's sarcoma-associated herpesvirus

S Chandriani, D Ganem - Journal of virology, 2010 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV) is a B-lymphotropic herpesvirus strongly
linked to both lymphoproliferative diseases and Kaposi's sarcoma. The viral latency program …

MicroRNAs: expression, avoidance and subversion by vertebrate viruses

P Sarnow, CL Jopling, KL Norman, S Schütz… - Nature Reviews …, 2006 - nature.com
MicroRNAs (miRNAs), which can be expressed in a cell-type and tissue-specific manner,
can influence the activities of genes that control cell growth and differentiation. Viruses often …

KSHV microRNAs mediate cellular transformation and tumorigenesis by redundantly targeting cell growth and survival pathways

R Moody, Y Zhu, Y Huang, X Cui, T Jones… - PLoS …, 2013 - journals.plos.org
Kaposi's sarcoma-associated herpesvirus (KSHV) is causally linked to several human
cancers, including Kaposi's sarcoma, primary effusion lymphoma and multicentric …

Virus-encoded microRNAs: novel regulators of gene expression

V Nair, M Zavolan - Trends in microbiology, 2006 - cell.com
MicroRNAs (miRNAs) are a class of small RNAs that have recently been recognized as
major regulators of gene expression. They influence diverse cellular processes ranging from …

Structure and function of latency-associated nuclear antigen

SC Verma, K Lan, E Robertson - Kaposi Sarcoma Herpesvirus: New …, 2007 - Springer
Latency-associated nuclear antigen (LANA) encoded by open reading frame 73 (ORF73) is
the major latent protein expressed in all forms of KSHV-associated malignancies. LANA is a …

Upregulation of the TLR3 pathway by Kaposi's sarcoma-associated herpesvirus during primary infection

J West, B Damania - Journal of virology, 2008 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV) is associated with several different human
malignancies, including Kaposi's sarcoma, primary effusion lymphoma, and multicentric …

Transcriptional origin of Kaposi's sarcoma-associated herpesvirus microRNAs

X Cai, BR Cullen - Journal of virology, 2006 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV) encodes 11 distinct microRNAs, all of
which are found clustered within the major latency-associated region of the KSHV genome …