Background Parkinson's disease (PD) is the second most common neurodegenerative
disease, and is characterized by accumulation of α-synuclein (α-syn). Neuroinflammation …

Simple Summary Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
responsible for the pandemic coronavirus disease-2019 (COVID-19), which can lead to …

Insufficient autophagy during critical illness is at least partly explained by feeding-induced
suppression. This may explain why early enhanced nutrition failed to benefit critically ill …

Carbon black nanoparticles (CBNPs) and cadmium (Cd) are major components of various
air pollutants and cigarette smoke. Autophagy and inflammation both play critical roles in …

Our paper describes the production and characterization of inhalable microparticles loaded
with nanoparticles for the lung administration of rapamycin (Rapa). In detail, core–shell …

Spermidine, a natural polyamine, has been proven antioxidant function, but its pathway and
mechanism of action remain unclear. Based on the oxidative stress model by 3 …

One of the toxic side effects of methotrexate (MTX) is enteritis. Aucubin, an iridoid glycoside
derived from traditional medicinal herbs, has been proven to have anti‐inflammation, anti …

Pathogens were a major driver of genetic adaptation during human evolution. Viruses in
particular were a dominant driver of adaptation in the thousands of proteins that physically …

Background Sepsis is a major medical condition that contributes to substantial morbidity and
mortality rates worldwide. Research to better understand and manage these complex …

Objective: To study the structure of BRAP-1, an acidic polysaccharide from Brassica rapa L.
and its effect and mechanism on lipopolysaccharide (LPS)-induced lung injury in mice …