Summary Abstract Olmesartan medoxomil (Olmetec®, Benicar®) is an angiotensin II type 1 (AT 1) receptor antagonist (angiotensin receptor blocker [ARB]) that inhibits the actions of …
Y Hu, L Liang, S Liu, JY Kung… - The Journal of Clinical …, 2023 - Wiley Online Library
Studies have shown that angiotensin converting enzyme inhibitors (ACEIs) are superior in primary and secondary prevention for cardiac mortality and morbidity to angiotensin receptor …
P Pongpanich, P Pitakpaiboonkul… - … urology and nephrology, 2018 - Springer
Background The prevalence of hypertension and its associated complications are markedly growing. Most patients need more than one drug to achieve blood pressure (BP) target …
A Abd-El Bary, SSD Louis - Journal of Drug Delivery Science and …, 2014 - Elsevier
This work aims to improve the dissolution of the poorly water soluble drug olmesartan medoxomil by using the surface solid dispersion (SSD) technique. Insoluble carriers, namely …
SA Yarows, S Oparil, S Patel, H Fang, J Zhang - Advances in therapy, 2008 - Springer
Introduction Patients with stage 2 hypertension require large absolute reductions in blood pressure (BP) to achieve recommended BP goals. Combination therapy with the direct renin …
IA Darwish, TA Wani, NY Khalil, AA Al-Shaikh… - Chemistry Central …, 2012 - Springer
A novel 96-microwell-based spectrophotometric assay has been developed and validated for determination of olmesartan medoxomil (OLM) in tablets. The formation of a colored …
G Kourlaba, F Gialama, K Tsioufis… - International Journal of …, 2016 - Elsevier
The objective of the present study was to systematically review the clinical and economic outcomes of olmesartan as monotherapy or in combination with other antihypertensive …
BJ Epstein, ME Roberts - American journal of therapeutics, 2009 - journals.lww.com
Calcium channel blockers (CCBs) play a vital role in the management of hypertension. Peripheral edema is the most common side effect reported with CCB monotherapy …
IS Sohn, CJ Kim, BH Oh, TJ Hong, CG Park… - American Journal of …, 2016 - Springer
Background This study was to evaluate the efficacy and safety of triple fixed-dose combination (FDC) therapy with olmesartan medoxomil (OM) 20 mg, amlodipine (AML) 5 …