[HTML][HTML] PI3K/Akt/Nrf2 mediated cellular signaling and virus-host interactions: latest updates on the potential therapeutic management of SARS-CoV-2 infection

VS Lekshmi, K Asha, M Sanicas, A Asi… - Frontiers in Molecular …, 2023 - frontiersin.org
The emergence and re-emergence of viral diseases, which cause significant global mortality
and morbidity, are the major concerns of this decade. Of these, current research is focused …

[HTML][HTML] D-dimer levels and characteristics of lymphocyte subsets, cytokine profiles in peripheral blood of patients with severe COVID-19: A systematic review and …

H Zhang, H Wu, D Pan, W Shen - Frontiers in Medicine, 2022 - frontiersin.org
Purpose: A series of complications caused by severe Covid-19 can significantly affect short-
term results. Therefore, early diagnosis is essential for critically COVID-19 patients. we …

[HTML][HTML] Hydroxypropyl-beta-cyclodextrin (HP-BCD) inhibits SARS-CoV-2 replication and virus-induced inflammatory cytokines

BB Bezerra, GPD da Silva, SVA Coelho, IA Correa… - Antiviral Research, 2022 - Elsevier
COVID-19 is marked by extensive damage to the respiratory system, often accompanied by
systemic manifestations, due to both viral cytopathic effects and hyperinflammatory …

[HTML][HTML] Circulating extracellular particles from severe COVID-19 patients show altered profiling and innate lymphoid cell-modulating ability

D Forte, RM Pellegrino, S Trabanelli, T Tonetti… - Frontiers in …, 2023 - frontiersin.org
Introduction Extracellular vesicles (EVs) and particles (EPs) represent reliable biomarkers
for disease detection. Their role in the inflammatory microenvironment of severe COVID-19 …

[HTML][HTML] Photobiomodulation improves serum cytokine response in mild to moderate COVID-19: The first randomized, double-blind, placebo controlled, pilot study

SM Marashian, M Hashemian, M Pourabdollah… - Frontiers in …, 2022 - frontiersin.org
Background Because the major event in COVID-19 is the release of pre-and inflammatory
cytokines, finding a reliable therapeutic strategy to inhibit this release, help patients manage …

Th-1, Th-2, Th-9, Th-17, Th-22 type cytokine concentrations of critical COVID-19 patients after treatment with Remdesivir

K Kalantar, AG Talepoor, ME Vakili, N Karami, M Kalani… - Immunobiology, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rapidly spread around the
world causing a pandemic known as coronavirus disease 2019 (COVID-19). Cytokine storm …

[HTML][HTML] Comparison of systemic inflammatory profiles in COVID-19 and community-acquired pneumonia patients: a prospective cohort study

ED Ibáñez-Prada, M Fish, YV Fuentes, IG Bustos… - Respiratory …, 2023 - Springer
Background Inflammatory responses contribute to tissue damage in COVID-19 and
community-acquired pneumonia (CAP). Although predictive values of different inflammatory …

Routine laboratory parameters, including complete blood count, predict COVID-19 in-hospital mortality in geriatric patients

F Olivieri, J Sabbatinelli, AR Bonfigli, R Sarzani… - Mechanisms of Ageing …, 2022 - Elsevier
To reduce the mortality of COVID-19 older patients, clear criteria to predict in-hospital
mortality are urgently needed. Here, we aimed to evaluate the performance of selected …

[HTML][HTML] Differential expression of biomarkers in saliva related to SARS-CoV-2 infection in patients with mild, moderate and severe COVID-19

L Verdiguel-Fernández, R Arredondo-Hernández… - BMC infectious …, 2023 - Springer
Background Severe COVID-19 is a disease characterized by profound dysregulation of the
innate immune system. There is a need to identify highly reliable prognostic biomarkers that …

[HTML][HTML] Dynamics of cytokine, SARS-CoV-2-specific IgG, and neutralizing antibody levels in COVID-19 patients treated with convalescent plasma

P Pratedrat, D Intharasongkroh, J Chansaenroj… - Diseases, 2023 - mdpi.com
Coronavirus disease 2019 (COVID-19) is a contagious illness worldwide. While guidelines
for the treatment of COVID-19 have been established, the understanding of the relationship …