SARS-CoV-2 spike protein: pathogenesis, vaccines, and potential therapies

AM Almehdi, G Khoder, AS Alchakee, AT Alsayyid… - Infection, 2021 - Springer
Purpose COVID-19 pandemic has emerged as a result of infection by the deadly pathogenic
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), causing enormous threats …

[HTML][HTML] A comprehensive review on pharmacologic agents, immunotherapies and supportive therapeutics for COVID-19

K Sharun, R Tiwari, MI Yatoo, S Natesan, D Megawati… - Narra J, 2022 - ncbi.nlm.nih.gov
The emergence of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has affected many countries throughout …

The rise of SARS-CoV-2 variants and the role of convalescent plasma therapy for management of infections

M Moubarak, KI Kasozi, HF Hetta, HM Shaheen, A Rauf… - Life, 2021 - mdpi.com
Novel therapies for the treatment of COVID-19 are continuing to emerge as the SARS-Cov-2
pandemic progresses. PCR remains the standard benchmark for initial diagnosis of COVID …

Pulmonary drug delivery: an effective and convenient delivery route to combat COVID-19

S Alipour, L Mahmoudi, F Ahmadi - Drug delivery and translational …, 2023 - Springer
The recent outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China has spread
rapidly around the world, leading to a widespread and urgent effort to develop and use …

A simplified SARS-CoV-2 pseudovirus neutralization assay

G Donofrio, V Franceschi, F Macchi, L Russo, A Rocci… - Vaccines, 2021 - mdpi.com
COVID-19 is an ongoing pandemic caused by the highly infectious coronavirus SARS-CoV-
2 that is engaging worldwide scientific research to find a timely and effective eradication …

COVID‐19: risk factors associated with infectivity and severity

N Fadl, E Ali, TZ Salem - Scandinavian Journal of Immunology, 2021 - Wiley Online Library
COVID‐19 is highly transmissible; however, its severity varies from one individual to
another. Variability among different isolates of the virus and among its receptor (ACE2) may …

Regulation of m6A methylation as a new therapeutic option against COVID-19

C Zannella, L Rinaldi, G Boccia, A Chianese… - Pharmaceuticals, 2021 - mdpi.com
The rapid spread of SARS-CoV-2 and the resulting pandemic has led to a spasmodic search
for approaches able to limit the diffusion of the disease. The epigenetic machinery has …

[HTML][HTML] Biomimetic nanoplasmonic sensor for rapid evaluation of neutralizing SARS-CoV-2 monoclonal antibodies as antiviral therapy

R Batool, M Soler, F Colavita, L Fabeni… - Biosensors and …, 2023 - Elsevier
Monoclonal antibody (mAb) therapy is one of the most promising immunotherapies that have
shown the potential to prevent or neutralize the effects of COVID-19 in patients at very early …

Development of a cell-based SARS-CoV-2 pseudovirus neutralization assay using imaging and flow cytometry analysis

JR Izac, EJ Kwee, L Tian, E Elsheikh… - International Journal of …, 2023 - mdpi.com
COVID-19 is an ongoing, global pandemic caused by the novel, highly infectious SARS-CoV-
2 virus. Efforts to mitigate the effects of SARS-CoV-2, such as mass vaccination and …

An in-depth in silico and immunoinformatics approach for designing a potential multi-epitope construct for the effective development of vaccine to combat against …

A Al Saba, M Adiba, P Saha, MI Hosen… - Computers in biology …, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the latest of the several
viral pathogens that have acted as a threat to human health around the world. Thus, to …