The neurodevelopmental disabilities of those who were born prematurely have been well
described, yet the underlying alterations in brain development that lead to these changes …

Neurodevelopmental outcomes are impaired in survivors of critical congenital heart disease
(CHD) in several developmental domains including motor, cognitive and sensory outcomes …

OBJECTIVE: Small head circumferences and white matter injury in the form of periventricular
leukomalacia have been observed in populations of infants with severe forms of congenital …

Background—Abnormalities on magnetic resonance imaging scans are common both
before and after surgery for congenital heart disease in early infancy. The aim of this study …

BACKGROUND: New intraparenchymal brain injury on magnetic resonance imaging is
observed in 36% to 73% of neonates after cardiac surgery with cardiopulmonary bypass …

Perinatal care advances emerging over the past twenty years have helped to diminish the
mortality and severe neurological morbidity of extremely and very preterm neonates (eg …

Patients with complex congenital heart disease are at risk for neurodevelopmental
impairments. Evidence suggests that brain maturation can be delayed and pre-and …

Background Adverse neurodevelopmental outcomes are observed in up to 50% of infants
after complex cardiac surgery. We sought to determine the association of perioperative …

2 Introduction data–to place the abnormality assessed within the wider context of
morphogenesis. The symptomatology of imaging–the very core of each chapter–is …

Objective Hypoxic-ischemic white mater brain injury commonly occurs in neonates with
hypoplastic left heart syndrome (HLHS). Approximately one half of HLHS survivors will …