Tissue engineering is a rapidly-growing approach to replace and repair damaged and
defective tissues in the human body. Every year, a large number of people require bone …

Fibrosis occurs when there is an imbalance in extracellular matrix (ECM) deposition and
degradation. Excessive ECM deposition results in scarring and thickening of the affected …

In recent years, the occurrence of a wide variety of drug-resistant diseases has led to an
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …

Bone morphogenetic proteins (BMPs) are members of the TGF-β superfamily and have
diverse functions during development and organogenesis. BMPs play a major role in …

Bone morphogenetic proteins (BMPs) are members of the TGF-β superfamily and play a
critical role in skeletal development, bone formation and stem cell differentiation. Disruptions …

Although bone morphogenetic proteins (BMPs) initially showed effective induction of ectopic
bone growth in muscle, it has since been determined that these proteins, as members of the …

Promoting osteogenic differentiation and efficacious bone regeneration have the potential to
revolutionize the treatment of orthopaedic and musculoskeletal disorders. Mesenchymal …

Molecular signals in the form of growth factors are the main modulators of cell behavior.
However, the use of growth factors in tissue engineering has several drawbacks, including …

The bone morphogenetic proteins (BMPs) are cytokines of the transforming growth factor
beta family. Some BMPs such as BMP-2, BMP-7 and BMP-9 play a major role in the bone …

Bone morphogenetic proteins (BMPs) constitute the largest subdivision of the transforming
growth factor (TGF)-β family of ligands and exert most of their effects through the canonical …