Necrostatin-1 and necroptosis inhibition: Pathophysiology and therapeutic implications
L Cao, W Mu - Pharmacological research, 2021 - Elsevier
Abstract Necrostatin-1 (Nec-1) is a RIP1-targeted inhibitor of necroptosis, a form of
programmed cell death discovered and investigated in recent years. There are already …
programmed cell death discovered and investigated in recent years. There are already …
[HTML][HTML] Prognostic value of leukocytosis and lymphopenia for coronavirus disease severity
To evaluate lymphopenia as a marker for coronavirus disease severity, we conducted a
meta-analysis of 10 studies. Severe illness was associated with lower lymphocyte and …
meta-analysis of 10 studies. Severe illness was associated with lower lymphocyte and …
[HTML][HTML] Natural killer cell dysfunction and its role in COVID-19
When facing an acute viral infection, our immune systems need to function with finite
precision to enable the elimination of the pathogen, whilst protecting our bodies from …
precision to enable the elimination of the pathogen, whilst protecting our bodies from …
[PDF][PDF] Dexamethasone for COVID-19? Not so fast
TC Theoharides, P Conti - J Biol Regul Homeost Agents, 2020 - researchgate.net
Recent announcements indicated, without sharing any distinct published set of results, that
use of the corticosteroid dexamethasone in a large trial in the UK apparently reduced …
use of the corticosteroid dexamethasone in a large trial in the UK apparently reduced …
Proinflammatory cytokines in the olfactory mucosa result in COVID-19 induced anosmia
A Torabi, E Mohammadbagheri… - ACS chemical …, 2020 - ACS Publications
Studies have found increased rates of dysosmia in patients with Novel Coronavirus disease
2019 (COVID-19). However, the mechanism that causes olfactory loss is unknown. The …
2019 (COVID-19). However, the mechanism that causes olfactory loss is unknown. The …
[HTML][HTML] COVID 19: a clue from innate immunity
D Birra, M Benucci, L Landolfi, A Merchionda, G Loi… - Immunologic …, 2020 - Springer
The recent COVID-19 pandemic has had a significant impact on our lives and has rapidly
expanded to reach more than 4 million cases worldwide by May 2020. These cases are …
expanded to reach more than 4 million cases worldwide by May 2020. These cases are …
A comprehensive review of manifestations of novel coronaviruses in the context of deadly COVID-19 global pandemic
Since December 2019, the global pandemic caused by the highly infectious novel
coronavirus 2019-nCoV (COVID-19) has been rapidly spreading. As of April 2020, the …
coronavirus 2019-nCoV (COVID-19) has been rapidly spreading. As of April 2020, the …
COVID-19 and cancer: From basic mechanisms to vaccine development using nanotechnology
HJ Han, C Nwagwu, O Anyim, C Ekweremadu… - International …, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is a global pandemic which has induced …
syndrome coronavirus 2 (SARS-CoV-2), is a global pandemic which has induced …
COVID-19 pandemic: an overview of epidemiology, pathogenesis, diagnostics and potential vaccines and therapeutics
At the time of writing this review, severe acute respiratory coronavirus syndrome-2 (SARS-
CoV-2) has infected more than 2,355,853 patients and resulted in more than 164,656 deaths …
CoV-2) has infected more than 2,355,853 patients and resulted in more than 164,656 deaths …
Baricitinib, a drug with potential effect to prevent SARS-COV-2 from entering target cells and control cytokine storm induced by COVID-19
X Zhang, Y Zhang, W Qiao, J Zhang, Z Qi - International …, 2020 - Elsevier
In December 2019, a novel coronavirus pneumonia (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) suddenly broke out in China and rapidly …
respiratory syndrome coronavirus 2 (SARS-CoV-2) suddenly broke out in China and rapidly …