Previous interest in high-density lipoproteins (HDLs) focused on their possible protective
role in atherosclerotic cardiovascular disease (ASCVD). Evidence from genetic studies and …

There have been significant advances, particularly over the last 20 years, in the identification
of non-coding RNAs (ncRNAs) and their pathophysiological role in a wide range of disease …

Idiopathic pulmonary fibrosis (IPF) is a progressive and ultimately fatal disease. Recent
findings have shown a marked metabolic reprogramming associated with changes in …

MicroRNAs (miRNAs) are secreted from cells as either protein-bound or enclosed in
extracellular vesicles. Circulating liver-derived miRNAs are modifiable by weight-loss or …

AgRP neurons drive hunger, and excessive nutrient intake is the primary driver of obesity
and associated metabolic disorders. While many factors impacting central regulation of …

Metabolic-associated fatty liver disease (MAFLD) is characterized by hepatic steatosis
accompanied by one of three features: overweight or obesity, T2DM, or lean or normal …

Fluoride-induced liver injury seriously endangers human and animal health and animal food
safety, but the underlying mechanism remains unclear. This study aims to explore the …

One of the major organs in the body with multiple functions is the liver. It plays a central role
in the transformation of macronutrients and clearance of chemicals and drugs. The serum …

Abstract Purpose of Review Non-coding RNAs (ncRNAs) including microRNAs (miRNAs)
and circular RNAs (circRNAs) are pivotal regulators of mRNA and protein expression that …

The liver holds central roles in detoxification, energy metabolism, and whole body
homeostasis but can develop malignant phenotypes when being chronically overwhelmed …