Nowadays, about 150 natural products comprising an allenic or cumulenic structure are
known. The chemistry of these compounds has turned out to be a very attractive and prolific …

While one-carbon central chirality of organic molecules has been recognized and
extensively studied for more than a century, far less attention has been paid to three-carbon …

Allenes have proven themselves to be valuable building blocks toward complex molecular
targets, revealing novel applications in natural product synthesis, pharmaceutical chemistry …

The C–F bond cleavage and C–C bond formation (ie, carbodefluorination) of readily
accessible (per) fluoroalkyl groups constitutes an atom-economical and efficient route to …

An efficient Rh (III)-catalyzed stepwise ortho allylation of N-methoxybenzamides 1 with
polysubstituted allenes is reported. This C–H functionalization involving allenes is …

A MnI‐catalyzed regioselective C− H allenylation is reported that allows a broad range of 2‐
allenylindoles to be synthesized regioselectively on a gram scale under simple conditions …

The reactivity of allenes in transition‐metal‐catalyzed C− H activation chemistry is governed
by the formation of either alkenyl–metal (M–alkenyl) or metal–π‐allyl intermediates …

The general enantioselective catalytic synthesis of axially chiral 1, 3-disubstituted allenes
from readily available racemic propargylic alcohol derivatives remains a long-standing …

The general enantioselective synthesis of axially chiral disubstituted allenes from prochiral
starting materials remains a long-standing challenge in organic synthesis. Here, we report …

We report that chiral bicyclic guanidine 1 is found to catalyze the isomerization of alkynes to
chiral allenes with high enantioselectivities. This Brønsted base catalyzed 1, 3-proton shift …