The RTS, S vaccine has recently been recommended for implementation as a childhood
vaccine in regions with moderate-to-high malaria transmission. We discuss mechanisms of …

Malaria is a mosquito-borne disease caused by protozoan parasites of the genus
Plasmodium. Despite significant declines in malaria-attributable morbidity and mortality over …

Plasmodium spp. is the etiological agent of malaria, a life-threatening parasitic disease
transmitted by infected mosquitoes. Malaria remains a major global health challenge …

Malaria and schistosomiasis are two major parasitic diseases that remain leading causes of
morbidity and mortality worldwide. Co-infections of these two parasites are common in the …

Aim The review summarizes the recent empirical evidence on the efficacy, safety, and
community perception of malaria vaccines in Africa. Methods Academic Search Complete …

Malaria remains one of the biggest health problems in the world. While significant reductions
in malaria morbidity and mortality had been achieved from 2000 to 2015, the favorable trend …

Mouse models are useful for the early down-selection of malaria vaccine candidates. The
Walter Reed Army Institute of Research has optimized a transgenic Plasmodium berghei …

Background A blood-stage Plasmodium falciparum malaria vaccine would provide a second
line of defence to complement partially effective or waning immunity conferred by the …

Background The first licensed malaria vaccine, RTS, S/AS01 E, confers moderate protection
against symptomatic disease. Because many malaria infections are asymptomatic, we …

While challenges remain in malaria control towards elimination, new guidelines and recently
approved vaccines offer hope. Monitoring for continued vaccine and chemoprevention …