[HTML][HTML] Diabetes mellitus: Classification, mediators, and complications; A gate to identify potential targets for the development of new effective treatments

SA Antar, NA Ashour, M Sharaky, M Khattab… - Biomedicine & …, 2023 - Elsevier
Nowadays, diabetes mellitus has emerged as a significant global public health concern with
a remarkable increase in its prevalence. This review article focuses on the definition of …

Oxidative stress and NRF2/KEAP1/ARE pathway in diabetic kidney disease (DKD): new perspectives

DM Tanase, EM Gosav, MI Anton, M Floria… - Biomolecules, 2022 - mdpi.com
Diabetes mellitus (DM) is one of the most debilitating chronic diseases worldwide, with
increased prevalence and incidence. In addition to its macrovascular damage, through its …

Molecular mechanisms of diabetic kidney disease

J Rico-Fontalvo, G Aroca, J Cabrales… - International Journal of …, 2022 - mdpi.com
The inflammatory component of diabetic kidney disease has become of great interest in
recent years, with genetic and epigenetic variants playing a fundamental role in the initiation …

Tubular injury in diabetic kidney disease: molecular mechanisms and potential therapeutic perspectives

Y Wang, M Jin, CK Cheng, Q Li - Frontiers in Endocrinology, 2023 - frontiersin.org
Diabetic kidney disease (DKD) is a chronic complication of diabetes and the leading cause
of end-stage renal disease (ESRD) worldwide. Currently, there are limited therapeutic drugs …

[PDF][PDF] Association of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio with diabetic kidney disease in Chinese patients with type 2 diabetes: a cross …

L Li, Q Shen, S Rao - Therapeutics and Clinical Risk Management, 2022 - Taylor & Francis
Purpose The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR)
have been extensively studied in a variety of diseases. However, research on their …

Mineralocorticoid receptor-associated mechanisms in diabetic kidney disease and clinical significance of mineralocorticoid receptor antagonists

CW Mende, R Samarakoon, PJ Higgins - American Journal of …, 2023 - karger.com
Background: Diabetic kidney disease (DKD) is a common disorder with multiple serious
clinical implications, including an increased risk of end-stage kidney disease (ESKD) …

Exosomal microRNAs: potential nanotherapeutic targets for diabetic kidney disease

L Han, X Cai, H Zhou - Nanomedicine, 2023 - Taylor & Francis
Diabetic kidney disease (DKD) is a primary cause for end-stage renal disease, but no
specific therapeutic approaches exist. Exosomal miRNAs, a key functional cargo of …

[HTML][HTML] Enfermedad renal diabética: puesta al día

J Rico Fontalvo, LC Vázquez Jiménez… - Anales de la Facultad …, 2022 - scielo.iics.una.py
RESUMEN Introducción: La Diabetes Mellitus (DM) es una enfermedad inflamatoria
sistémica de alta prevalencia e incidencia a nivel mundial. Dentro de las complicaciones …

[HTML][HTML] Therapeutic efficacy of dapagliflozin on diabetic kidney disease in rats

H Yang, Z Mei, W Chen, Y Pan, L Liu, R Zhao… - International …, 2022 - Elsevier
Aim Diabetic kidney disease (DKD) is one of the severe microvascular complications of type
2 diabetes mellitus (T2DM), which eventually leads to irreversible renal damage and …

Long non-coding RNAs in the pathogenesis of diabetic kidney disease

M Hu, Q Ma, B Liu, Q Wang, T Zhang… - Frontiers in cell and …, 2022 - frontiersin.org
Diabetic kidney disease (DKD) is one of the major microvascular complications of diabetes
mellitus, with relatively high morbidity and mortality globally but still in short therapeutic …