Metabolic profiling to determine bactericidal or bacteriostatic effects of new natural products using isothermal microcalorimetry

K Cirnski, J Coetzee, J Herrmann, R Müller - JoVE (Journal of Visualized …, 2020 - jove.com
Due to the global threat of rising antimicrobial resistance, novel antibiotics are urgently
needed. We investigate natural products from Myxobacteria as an innovative source of such …

[HTML][HTML] Efficacy of Experimental Mouth Rinses on Caries-Related Biofilms in vitro

J Steiger, O Braissant, T Waltimo… - Frontiers in Oral …, 2021 - frontiersin.org
This study assessed the efficacy of tin and Polyethylenglycol (PEG-3) tallow
aminopropylamine in different concentrations on Streptococcus mutans (S. mutans) biofilms …

[HTML][HTML] Microcalorimetry—versatile method of describing bacterial growth

MIG Popa, A Cursaru, B Serban, B Cretu, AA Muntean… - Applied Sciences, 2021 - mdpi.com
Featured Application A detailed investigation (including kinetic analysis) of the reproductible
thermal signal produced by bacterial growth can lead to the development of alternative …

Polymyxin B stabilized DNA micelles for sustained antibacterial and antibiofilm activity against P. aeruginosa

AS Antunes de Sousa, V Borøy, AH Bæverud, K Julin… - 2023 - munin.uit.no
Nucleic acid-based materials showcase an increasing potential for antimicrobial drug
delivery. Although numerous reports on drug-loaded DNA nanoparticles outline their pivotal …

Accessory genes define species-specific pathways to antibiotic resistance.

L Dillon, NJ Dimonaco, CJ Creevey - bioRxiv, 2023 - biorxiv.org
Background: The rise of antimicrobial resistance (AMR) is a growing concern globally and a
deeper understanding of AMR gene carriage vs usage is vital for future responses to reduce …

Activity of Antibiotics against Burkholderia cepacia complex in Artificial Sputum Medium

A Shukla, S Rodriguez, T Brennan-Krohn - bioRxiv, 2023 - biorxiv.org
Burkholderia cepacia complex (Bcc) is a collection of intrinsically drug-resistant gram-
negative bacteria that cause life-threatening pulmonary disease in people with cystic fibrosis …

Assessing the evolutionary robustness of anti-biofilm combination therapy

M Bové - 2022 - biblio.ugent.be
Besides the well-known problems associated with antibiotic resistance, treatment of
bacterial infections is hampered by the fact that bacteria often reside in biofilms. One of the …

Metabolic flux fingerprinting differentiates planktonic and biofilm states of Pseudomonas aeruginosa and Staphylococcus aureus

M Lichtenberg, KN Kragh, B Fritz, J Bier-Kirkegaard… - BioRxiv, 2020 - biorxiv.org
The challenges of defining the biofilm phenotype has been clear for decades. Many
biomarkers for biofilm are known, but methods for identifying these are often invasive and/or …

[PDF][PDF] Jiao Liu1, Min Shao2, Qianghong Xu3, Fen Liu4, Xiaojun Pan1, Jianfeng Wu5, Lihong Xiong6, Yueming Wu7, Mi Tian8, Jianying Yao9, Sisi Huang1, Lidi …

YL TaoWang, W Li, Y Xu, J Teboul10, D Chen - 2022 - annalsofintensivecare.springeropen …
Background: The mortality of extensively drug‑resistant Gram‑negative (XDR GN) bacilli‑
induced ventilator‑associ‑ated pneumonia (VAP) is extremely high. The purpose of this …

Development of DNA Nanoparticles with Properties for Enhanced Biofilm Uptake

V Borøy - 2022 - munin.uit.no
Microbial biofilms account for up to 80% of all bacterial infections. They are described as
small structural communities of bacteria which are embedded in a self-produced …