The immunosuppressive molecule programmed death-ligand 1 (PD-L1) is frequently
upregulated in human cancers. Binding of PD-L1 to its receptor, programmed death-1 (PD …

Diabetes is a group of chronic diseases with blood glucose imbalance, and long-term
hyperglycaemia causes sustained damage to various organs of the body, resulting in …

Altered energy metabolism is one of the hallmarks of tumorigenesis and essential for
fulfilling the high demand for metabolic energy in a tumor through accelerating glycolysis …

Background Gastric cancer (GC) is one of the most prevalent malignant tumors of the
digestive system. As a hallmark of cancer, energy-related metabolic reprogramming is …

Endometrial cancer (EC) is a common malignancy of the female reproductive system, with
an escalating incidence. Recurrent/metastatic EC presents a poor prognosis. The interaction …

Cancer heterogeneity and drug resistance remain pivotal obstacles in effective cancer
treatment and management. One major contributor to these challenges is epigenetic …

Lymph node metastases are commonly observed in diverse malignancies where they
promote cancer progression and poor outcomes, although the molecular basis is …

Immune checkpoint blockade therapy has revolutionized the field of cancer treatment,
leading to durable responses in patients with advanced and metastatic cancers where …

Background: Neutrophil extracellular traps (NETs) are closely associated to tumorigenesis
and development. However, the relationship between NETs-related long non-coding RNAs …

Tumor-associated macrophages (TAMs) mainly exhibit the characteristics of M2-type
macrophages, and the regulation of TAM polarization is a new target for cancer therapy …