[HTML][HTML] Homeostasis, inflammation, and disease susceptibility

ME Kotas, R Medzhitov - Cell, 2015 - cell.com
While modernization has dramatically increased lifespan, it has also witnessed the
increasing prevalence of diseases such as obesity, hypertension, and type 2 diabetes. Such …

Polycystic ovary syndrome: an evolutionary adaptation to lifestyle and the environment

J Parker, C O'brien, J Hawrelak, FL Gersh - International journal of …, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is increasingly recognized as a complex metabolic
disorder that manifests in genetically susceptible women following a range of negative …

Comprehending the body in the era of the epigenome

M Lock - Current Anthropology, 2015 - journals.uchicago.edu
This paper suggests that it is urgent for anthropologists to respond to a current move in
epigenetics in which nature and nurture are no longer understood as dichotomous …

Maternal capital and the metabolic ghetto: an evolutionary perspective on the transgenerational basis of health inequalities

JCK Wells - American Journal of Human Biology: The Official …, 2010 - Wiley Online Library
There is particular interest in understanding socioeconomic and ethnic variability in health
status. The developmental origins of disease hypothesis emphasize the importance of …

Link between insulin resistance and hypertension: What is the evidence from evolutionary biology?

MS Zhou, A Wang, H Yu - Diabetology & metabolic syndrome, 2014 - Springer
Insulin resistance and hypertension are considered as prototypical “diseases of civilization”
that are manifested in the modern environment as plentiful food and sedentary life. The …

[HTML][HTML] The elevated susceptibility to diabetes in India: an evolutionary perspective

JCK Wells, E Pomeroy, SR Walimbe… - Frontiers in public …, 2016 - frontiersin.org
India has rapidly become a “diabetes capital” of the world, despite maintaining high rates of
under-nutrition. Indians develop diabetes at younger age and at lower body weights than …

An analysis of the interrelationship between maternal age, body mass index and racial origin in the development of gestational diabetes mellitus

M Makgoba, MD Savvidou… - BJOG: An International …, 2012 - Wiley Online Library
Please cite this paper as: Makgoba M, Savvidou M, Steer P. An analysis of the
interrelationship between maternal age, body mass index and racial origin in the …

[图书][B] The evolutionary biology of human body fatness: thrift and control

JCK Wells - 2010 - books.google.com
This comprehensive synthesis of current medical and evolutionary literature addresses key
questions about the role body fat plays in human biology. It explores how body energy …

Obesity and diabetes: from genetics to epigenetics

E Burgio, A Lopomo, L Migliore - Molecular biology reports, 2015 - Springer
Obesity is becoming an epidemic health problem. During the last years not only genetic but
also, and primarily, environmental factors have been supposed to contribute to the …

Inositol's and other nutraceuticals' synergistic actions counteract insulin resistance in polycystic ovarian syndrome and metabolic syndrome: state-of-the-art and future …

C Paul, AS Laganà, P Maniglio, O Triolo… - Gynecological …, 2016 - Taylor & Francis
The incidence of metabolic syndrome (MetS), type II diabetes (T2D) and polycystic ovarian
syndrome (PCOS) has been progressively increasing. Insulin resistance (InsR) seems to …