The epidemiology of inflammatory bowel disease: East meets west

WY Mak, M Zhao, SC Ng… - Journal of gastroenterology …, 2020 - Wiley Online Library
The incidence of inflammatory bowel diseases (IBD) in East has risen over the past decade
to become a global disease. The increasing number of studies on the incidence and course …

[HTML][HTML] Implications of sex differences in immunity for SARS-CoV-2 pathogenesis and design of therapeutic interventions

MJ Bunders, M Altfeld - Immunity, 2020 - cell.com
Men present more frequently with severe manifestations of coronavirus disease 2019
(COVID-19) and are at higher risk for death. The underlying mechanisms for these …

Inflammatory bowel disease in pregnancy clinical care pathway: a report from the American Gastroenterological Association IBD Parenthood Project Working Group

U Mahadevan, C Robinson, N Bernasko… - Inflammatory bowel …, 2019 - academic.oup.com
In the United States, approximately 0.5% of the population, or 1.6 million people, have
inflammatory bowel disease (IBD)—Crohn's disease (CD) and ulcerative colitis (UC). 1, 2 Of …

[HTML][HTML] Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis

F Hinrichsen, J Hamm, M Westermann, L Schröder… - Cell Metabolism, 2021 - cell.com
Hexokinases (HK) catalyze the first step of glycolysis limiting its pace. HK2 is highly
expressed in gut epithelium, contributes to immune responses, and is upregulated during …

Gender differences in inflammatory bowel disease

T Greuter, C Manser, V Pittet, SR Vavricka… - Digestion, 2020 - karger.com
Immune-mediated diseases typically show a female preponderance. Looking at all
autoimmune diseases combined, 8 of 10 patients are females. Although not as prominent …

Emerging pharmacotherapy for inflammatory bowel diseases

H Luo, G Cao, C Luo, D Tan, CT Vong, Y Xu… - Pharmacological …, 2022 - Elsevier
Inflammatory bowel disease (IBD) refers to a gamut of disorders that are characterized by
chronic intestinal inflammation, including ulcerative colitis (UC) and Crohn's disease (CD) …

The epidemiology of inflammatory bowel disease in Asia and Asian immigrants to Western countries

S Aniwan, P Santiago, EV Loftus Jr… - United European …, 2022 - Wiley Online Library
Inflammatory bowel disease (IBD), which comprises Crohn's disease and ulcerative colitis, is
an idiopathic inflammatory condition of the gastrointestinal tract. The incidence and …

Sex matters: impact on pathogenesis, presentation and treatment of inflammatory bowel disease

WA Goodman, IP Erkkila, TT Pizarro - Nature reviews Gastroenterology …, 2020 - nature.com
Inflammatory bowel disease (IBD), as do most chronic inflammatory disorders, displays
unique features and confers different risk factors in male and female patients. Importantly …

A 30-year trend analysis in the epidemiology of inflammatory bowel disease in the Songpa-Kangdong District of Seoul, Korea in 1986–2015

SH Park, YJ Kim, KH Rhee, YH Kim… - Journal of Crohn's …, 2019 - academic.oup.com
Abstract Background and Aims Although the incidence of inflammatory bowel disease [IBD]
is increasing in Asia, data on long-term epidemiological trends are limited. We performed a …

The rising burden of inflammatory bowel disease in Denmark over two decades: a nationwide cohort study

M Agrawal, HS Christensen, M Bøgsted, JF Colombel… - Gastroenterology, 2022 - Elsevier
Background & Aims Shifts in epidemiological stages of inflammatory bowel disease (IBD)
carry implications toward understanding IBD etiology and managing clinical care. We …