Pathological effects of nano-sized particles on the respiratory system

R Nho - Nanomedicine: Nanotechnology, Biology and Medicine, 2020 - Elsevier
Recent advances in nanotechnology have made significant progress in biomedical
sciences. However, there are growing concerns that exposure to naturally-occurring and …

Tissue remodelling in pulmonary fibrosis

L Knudsen, C Ruppert, M Ochs - Cell and tissue research, 2017 - Springer
Many lung diseases result in fibrotic remodelling. Fibrotic lung disorders can be divided into
diseases with known and unknown aetiology. Among those with unknown aetiology …

Computed tomography findings in acute exacerbation of idiopathic pulmonary fibrosis

M Akira, T Kozuka, S Yamamoto… - American journal of …, 2008 - atsjournals.org
Rationale: The serial computed tomography findings and prognosis of the acute
exacerbation of idiopathic pulmonary fibrosis (IPF) are not yet well defined in a larger …

Factor Xa: at the crossroads between coagulation and signaling in physiology and disease

K Borensztajn, MP Peppelenbosch, CA Spek - Trends in molecular …, 2008 - cell.com
Activated factor Xa (FXa) is traditionally known as an important player in the coagulation
cascade responsible for thrombin generation. Long considered a passive bystander, it is …

Functional Au nanoparticles for engineering and long-term CT imaging tracking of mesenchymal stem cells in idiopathic pulmonary fibrosis treatment

H Bao, S Cheng, X Li, Y Li, C Yu, J Huang, Z Zhang - Biomaterials, 2022 - Elsevier
Idiopathic pulmonary fibrosis (IPF) therapy has always been a big and long-standing
challenge in clinical practice due to the lack of miraculous medicine. Mesenchymal stem …

Bone morphogenetic protein-4 inhibitor gremlin is overexpressed in idiopathic pulmonary fibrosis

K Koli, M Myllärniemi, K Vuorinen, K Salmenkivi… - The American journal of …, 2006 - Elsevier
Idiopathic pulmonary fibrosis (IPF), ie, usual interstitial pneumonia in histopathology, is a
disease characterized by tissue destruction and active areas of fibroproliferation in the lung …

Oxidative stress, plasminogen activator inhibitor 1, and lung fibrosis

RM Liu - Antioxidants & redox signaling, 2008 - liebertpub.com
Fibrosis is characterized by excessive accumulation of extracellular matrix (ECM) in
basement membranes and interstitial tissues, resulting from increased synthesis or …

Potential contribution of alveolar epithelial type I cells to pulmonary fibrosis

M Kasper, K Barth - Bioscience reports, 2017 - portlandpress.com
Pulmonary fibrosis (PF) is characterized by inflammation and fibrosis of the interstitium and
destruction of alveolar histoarchitecture ultimately leading to a fatal impairment of lung …

Alveolar derecruitment and collapse induration as crucial mechanisms in lung injury and fibrosis

D Lutz, A Gazdhar, E Lopez-Rodriguez… - American journal of …, 2015 - atsjournals.org
Idiopathic pulmonary fibrosis (IPF) and bleomycin-induced pulmonary fibrosis are
associated with surfactant system dysfunction, alveolar collapse (derecruitment), and …

The role of PPARs in lung fibrosis

HF Lakatos, TH Thatcher, RM Kottmann… - PPAR …, 2007 - Wiley Online Library
Pulmonary fibrosis is a group of disorders characterized by accumulation of scar tissue in
the lung interstitium, resulting in loss of alveolar function, destruction of normal lung …