[HTML][HTML] The SARS-CoV-2 nucleocapsid protein and its role in viral structure, biological functions, and a potential target for drug or vaccine mitigation

Z Bai, Y Cao, W Liu, J Li - Viruses, 2021 - mdpi.com
The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the world
is still expanding. Thus, there is an urgent need to better understand this novel virus and find …

[HTML][HTML] Mutations of SARS-CoV-2 spike protein: Implications on immune evasion and vaccine-induced immunity

HM Mengist, AJK Kombe, D Mekonnen, A Abebaw… - Seminars in …, 2021 - Elsevier
Responsible for more than 4.9 million deaths so far, COVID-19, caused by SARS-CoV-2, is
instigating devastating effects on the global health care system whose impacts could be …

[HTML][HTML] The trans-omics landscape of COVID-19

P Wu, D Chen, W Ding, P Wu, H Hou, Y Bai… - Nature …, 2021 - nature.com
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency.
Various omics results have been reported for COVID-19, but the molecular hallmarks of …

Attenuating the effects of novel COVID-19 (SARS-CoV-2) infection-induced cytokine storm and the implications

AB Rowaiye, OA Okpalefe… - Journal of …, 2021 - Taylor & Francis
The COVID-19 pandemic constitutes an arduous global health challenge, and the
increasing number of fatalities calls for the speedy pursuit of a remedy. This review …

[HTML][HTML] Immunomodulatory role of interferons in viral and bacterial infections

P Mertowska, K Smolak, S Mertowski… - International journal of …, 2023 - mdpi.com
Interferons are a group of immunomodulatory substances produced by the human immune
system in response to the presence of pathogens, especially during viral and bacterial …

[HTML][HTML] Cytokines and microRNAs in SARS-CoV-2: What do we know?

FZ Rarani, B Rashidi, MHJN Abadi, MR Hamblin… - … Therapy-Nucleic Acids, 2022 - cell.com
The coronavirus disease 2019 (COVID-19) pandemic constitutes a global health
emergency. Currently, there are no completely effective therapeutic medications for the …

Obesity and COVID-19: mechanistic insights from adipose tissue

L Yu, X Zhang, S Ye, H Lian, H Wang… - The Journal of Clinical …, 2022 - academic.oup.com
Obesity is associated with an increase in morbidity and mortality from coronavirus disease
2019 (COVID-19). The risk is related to the cytokine storm, a major contributor to multiorgan …

[HTML][HTML] COVID-19 immunobiology: lessons learned, new questions arise

A Kaklamanos, K Belogiannis, P Skendros… - Frontiers in …, 2021 - frontiersin.org
There is strong evidence that COVID-19 pathophysiology is mainly driven by a
spatiotemporal immune deregulation. Both its phenotypic heterogeneity, spanning from …

Proteomics analysis of plasma-derived exosomes unveils the aberrant complement and coagulation cascades in dermatomyositis/polymyositis

S Meng, T Wang, Q Zhao, Q Hu, Y Chen… - Journal of Proteome …, 2022 - ACS Publications
Dermatomyositis and polymyositis (DM/PM) are systemic autoimmune diseases
characterized by proximal muscle weakness. The underlying pathogenetic mechanism of …

[HTML][HTML] COVID-19 signalome: Potential therapeutic interventions

K Lundstrom, A Hromić-Jahjefendić, E Bilajac… - Cellular signalling, 2023 - Elsevier
The COVID-19 pandemic has triggered intensive research and development of drugs and
vaccines against SARS-CoV-2 during the last two years. The major success was especially …