In the present study the synthesis and antinociceptive activity of bis-vinyl selenides, prepared via FeCl3 promoted reaction addition of diorganyl dichalcogenides to alkynes, is …
In this study, the antioxidant and antidepressant-like effects of α-(phenylselanyl) acetophenone (PSAP), an organoselenium compound, were investigated. To assess the in …
Abstract (E)-1, 2-Bis-chalcogen alkenes were stereoselectively prepared in good yields by the addition of diorganyl dichalcogenides to terminal alkynes using CuI/Zn/glycerol as a …
Evidence show that gamma-aminobutyric acid (GABA) receptors are involved in depression, so the aim of this study was to investigate the effect of nitrazepam as agonist of GABA A …
M Coppola, R Mondola - Medical Hypotheses, 2014 - Elsevier
Depression is a common brain disorder affecting about 350 million people worldwide. Although the pharmacological treatment currently available can produce benefits in the …
AL Braga, J Rafique - PATAI'S Chemistry of Functional Groups, 2009 - Wiley Online Library
Organoselenium compounds are known as antioxidants, antithyroid, antinociceptive, antidepressant, thioredoxin reductase (TrxR) mimetic agents with a variety of protective …