Age‐associated obesity and muscle atrophy (sarcopenia) are intimately connected and are
reciprocally regulated by adipose tissue and skeletal muscle dysfunction. During ageing …

In mammals, the white adipocyte is a cell type that is specialized for storage of energy (in the
form of triacylglycerols) and for energy mobilization (as fatty acids). White adipocyte …

Obesity is a growing health problem worldwide. It is associated with an increased
cardiovascular risk on the one hand of obesity itself and on the other hand of associated …

Obesity and ageing place a tremendous strain on the global healthcare system. Age-related
sarcopenia is characterized by decreased muscular strength, decreased muscle quantity …

The prevalence of overweight and obesity has reached epidemic proportions worldwide due
to increasingly pervasive obesogenic lifestyle changes. Obesity poses unprecedented …

Calorie restriction (CR), the reduction of dietary intake below energy requirements while
maintaining optimal nutrition, is the only known nutritional intervention with the potential to …

Age-dependent loss of skeletal muscle mass and function is a feature of sarcopenia, and
increases the risk of many aging-related metabolic diseases. Here, we report phenotypic …

Abstract Purpose of Review This review provides a comprehensive update on the definition,
assessment, epidemiology, pathophysiology, clinical implications, and therapeutic approach …

Apigenin is a flavonoid with antioxidant, anti-inflammatory, and anti-apoptotic activity. In this
study, the potential effects of apigenin on cardiometabolic diseases were investigated in vivo …

Obesity is associated with biological dysfunction in skeletal muscle. As a condition of obesity
accompanied by muscle mass loss and physical dysfunction, sarcopenic obesity (SO) has …