Recent advances in drug and nutrient transport across the blood-retinal barrier

Y Kubo, S Akanuma, K Hosoya - Expert Opinion on Drug …, 2018 - Taylor & Francis
Introduction: The blood-retinal barrier (BRB) is the barrier separating the blood and neural
retina, and transport systems for low-weight molecules at the BRB are expected to be useful …

Effect of amino acid enriched diets on hemolymph amino acid composition in honey bees

E Tafi, S Sagona, V Meucci, L Bortolotti… - Archives of Insect …, 2024 - Wiley Online Library
Amino acids (AAs) are an abundant class of nectar solutes, and they are involved in the
nectar attractiveness to flower visitors. Among the various AAs, proline is the most abundant …

Effects of dietary sports supplements on metabolite accumulation, vasodilation and cellular swelling in relation to muscle hypertrophy: A focus on “secondary” …

J Cholewa, E Trexler, F Lima-Soares… - Nutrition, 2019 - Elsevier
Increased blood flow via vasodilation, metabolite production, and venous pooling contribute
to the hyperemia and cellular swelling experienced during resistance training. It has been …

A Metabolomic Signature of Ischemic Stroke Showing Acute Oxidative and Energetic Stress

M Djite, JM Chao de la Barca, C Bocca, NM Gaye… - Antioxidants, 2023 - mdpi.com
Metabolomics is a powerful data-driven tool for in-depth biological phenotyping that could
help identify the specific metabolic profile of cryptogenic strokes, for which no precise cause …

Behavioral and inflammatory response in animals exposed to a low-pressure blast wave and supplemented with β-alanine

JR Hoffman, A Zuckerman, O Ram, O Sadot, JR Stout… - Amino Acids, 2017 - Springer
This study investigated the benefit of β-alanine (BA) supplementation on behavioral and
cognitive responses relating to mild traumatic brain injury (mTBI) and post-traumatic stress …

[HTML][HTML] Beta-alanine supplementation improved 10-km running time trial in physically active adults

JO Santana, MC De Freitas, DM Dos Santos… - Frontiers in …, 2018 - frontiersin.org
The purpose of this study was to investigate the effects of β-alanine supplementation on a 10
km running time trial and lactate concentration in physically active adults. Sixteen healthy …

Sub-chronic exposure to PhIP induces oxidative damage and DNA damage, and disrupts the amino acid metabolism in the colons of Wistar rats

X Zhao, Z Shao, X Zhou, Y Lin, J Guo, J Guo… - Food and Chemical …, 2021 - Elsevier
Heterocyclic amines (HCAs) are a group of mutagenic compounds produced during thermal
processing of protein-rich foods. One of the most abundant HCAs, 2-amino-1-methyl-6 …

The complexed crystal structure of dihydropyrimidinase reveals a potential interactive link with the neurotransmitter γ-aminobutyric acid (GABA)

YH Huang, CY Huang - Biochemical and Biophysical Research …, 2024 - Elsevier
Dihydropyrimidinase (DHPase) plays a crucial role in pyrimidine degradation, showcasing a
broad substrate specificity that extends beyond pyrimidine catabolism, hinting at additional …

A Comprehensive NMR Analysis of Serum and Fecal Metabolites in Familial Dysautonomia Patients Reveals Significant Metabolic Perturbations

SM Costello, AM Cheney, A Waldum, B Tripet… - Metabolites, 2023 - mdpi.com
Central metabolism has a profound impact on the clinical phenotypes and penetrance of
neurological diseases such as Alzheimer's (AD) and Parkinson's (PD) diseases …

A density functional theory investigation on norepinephrine interaction with amino acids and alcohols

AM Priya, B Aazaad, DM Biju - Journal of Molecular Structure, 2023 - Elsevier
Norepinephrine (NP) plays a key role in the behaviour of forebrain activities, acts as a
hormone and neurotransmitter in the central nervous system releases from the neurons of …