Parasitic diseases still compromise human health. Some of the currently available
therapeutic drugs have limitations considering their adverse effects, questionable efficacy …

Neglected tropical diseases (NTDs) are a significant global health problem. Additionally, anti-
protozoan treatments are toxic, and their therapeutic regimens require prolonged treatment …

diaminoacridines with reported antiplasmodial activity were coupled to different trans-
cinnamic acids, delivering a new series of conjugates inspired by the covalent bitherapy …

Background The clinical use of artemisinin-based combination therapies is threatened by
increasing failure rates due to the emergence and spread of multiple drug resistance genes …

New pyridine‐based chalcones 4a–h and pyrazolines 5a–h (N‐acetyl), 6a–h (N‐phenyl),
and 7a–h (N‐4‐chlorophenyl) were synthesized and evaluated by the National Cancer …

Malaria represents a major global health concern, primarily due to the emergence of
resistance against most currently available antimalarial drugs. This pressing issue …

This research aims to discover active compounds from the leaf extract from Cratoxylum
glaucum using the bioassay-guided isolation method. The multistage extraction of C …

Parasitic diseases including malaria, leishmaniasis, and trypanosomiasis have received
significant attention due to their severe health implications, especially in developing …

Background: Artemisinin-resistant parasites pose a danger to the efficacy of malaria
treatment. For a very long time, pharmaceutical companies have relied on plants to provide …