[HTML][HTML] Animal models for HIV/AIDS research

T Hatziioannou, DT Evans - Nature Reviews Microbiology, 2012 - nature.com
The AIDS pandemic continues to present us with unique scientific and public health
challenges. Although the development of effective antiretroviral therapy has been a major …

[HTML][HTML] Antiviral monoclonal antibodies: can they be more than simple neutralizing agents?

M Pelegrin, M Naranjo-Gomez, M Piechaczyk - Trends in microbiology, 2015 - cell.com
Monoclonal antibodies (mAbs) are increasingly being considered as agents to fight severe
viral diseases. So far, they have essentially been selected and used on the basis of their …

Passive neutralizing antibody controls SHIV viremia and enhances B cell responses in infant macaques

CT Ng, JP Jaworski, P Jayaraman, WF Sutton… - Nature medicine, 2010 - nature.com
Maternal HIV-1–specific antibodies are efficiently transferred to newborns, but their role in
disease control is unknown. We administered neutralizing IgG, including the human …

Autologous neutralizing antibodies increase with early antiretroviral therapy and shape HIV rebound after treatment interruption

E Esmaeilzadeh, B Etemad, CL Lavine… - Science translational …, 2023 - science.org
Early initiation of antiretroviral therapy (ART) alters viral rebound kinetics after analytic
treatment interruption (ATI) and may play a role in promoting HIV-1 remission. Autologous …

[HTML][HTML] Antibody-mediated prevention and treatment of HIV-1 infection

H Gruell, F Klein - Retrovirology, 2018 - Springer
Novel broadly neutralizing antibodies targeting HIV-1 hold promise for their use in the
prevention and treatment of HIV-1 infection. Pre-clinical results have encouraged the …

Elite control of HIV infection: implications for vaccine design

BM Baker, BL Block, AC Rothchild… - Expert opinion on …, 2009 - Taylor & Francis
Background:'Elite controllers' are rare HIV-infected individuals who are able to
spontaneously control HIV replication without medication, maintaining viral loads that are …

Blocking α4β7 integrin delays viral rebound in SHIVSF162P3-infected macaques treated with anti-HIV broadly neutralizing antibodies

I Frank, M Cigoli, MS Arif, MD Fahlberg… - Science translational …, 2021 - science.org
Anti-HIV broadly neutralizing antibodies (bNAbs) may favor development of antiviral
immunity by engaging the immune system during immunotherapy. Targeting integrin α4β7 …

Engineering broadly neutralizing antibodies for HIV prevention and therapy

CK Hua, ME Ackerman - Advanced drug delivery reviews, 2016 - Elsevier
A combination of advances spanning from isolation to delivery of potent HIV-specific
antibodies has begun to revolutionize understandings of antibody-mediated antiviral activity …

Vaccinal effect of HIV-1 antibody therapy: dream or reality?

M Naranjo-Gomez, M Pelegrin - Current Opinion in HIV and AIDS, 2023 - journals.lww.com
HIV-1 bNAbs can enhance adaptive host immune responses in PLWH. The challenge now
is to exploit these immunomodulatory properties to design optimized therapeutic …

Vaccinal effect of HIV-1 antibody therapy

M Naranjo-Gomez, M Pelegrin - Current Opinion in HIV and AIDS, 2019 - journals.lww.com
Vaccinal effect of HIV-1 antibody therapy : Current Opinion in HIV and AIDS Vaccinal effect of
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