Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …

Objective The objective of this article is to review abrocitinib, an oral Janus kinase (JAK) 1
inhibitor, for the treatment of patients with moderate-to-severe atopic dermatitis (AD). Data …

Background: Atopic dermatitis (AD) is a widely acquired, relapsing inflammatory skin
disease. Biologics are now widely used in patients with moderate-to-severe AD. Objective …

Abstract The Janus kinases or JAKs are a family of intracellular tyrosine kinases that play an
essential role in the signaling of numerous cytokines that have been implicated in the …

Иммуновоспалительные ревматические заболевания (ИВРЗ)-большая группа
патологических состояний, в основе которых лежит нарушение иммунологической …

Vitiligo is a skin disorder characterized by depigmentation of the skin due to a lack of
melanin. This condition affects men and woman of all ages and its incidence is not restricted …

Janus kinases (JAKs) are a group of intracytoplasmic tyrosine kinase proteins that bind to
the cytoplasmic part of the transmembrane cytokine receptors and regulate signaling. The …

Increasing understanding of cytokines as major drivers of immune‐mediated diseases has
revolutionized targeted treatments for these conditions. As the pathogenesis of autoimmune …

Introduction: Netherton syndrome (NS) is a rare and severe ichthyosis characterized by
superficial scaling, skin inflammation, a specific hair shaft defect, severe atopic …

The development of therapies for SARS-CoV-2 infection, based on virus biology and
pathology, and of large-and small-scale randomized controlled trials, have brought forward …