Worldwide nanotechnology development and application have fueled many scientific
advances, but technophilic expectations and technophobic demands must be …

Cancer is ranked as the second leading cause of death globally. Traditional cancer
therapies including chemotherapy are flawed, with off-target and on-target toxicities on the …

Research on the use of biodegradable polymers for drug delivery has been ongoing since
they were first used as bioresorbable surgical devices in the 1980s. For tissue engineering …

Clinically available medications face several hurdles that limit their therapeutic activity,
including restricted access to the target tissues due to biological barriers, low bioavailability …

Introduction During the last decades, the ever-increasing proportion of patients with cancer
has been led to serious concerns worldwide. Therefore, the development and use of novel …

Background Controlled release and targeted delivery of the drug payload are the two most
fascinating applications of nanoparticle-based systems explored in the recent past. The …

Bioresponsive polymers have been widely used in drug delivery because of their
degradability. For example, poly (disulfide) s with repeating disulfide bonds in the main …

To date, hydrogels have opened new prospects for potential applications for drug delivery.
The thermo-sensitive hydrogels have the great potential to provide more effective and …

Polymeric nanoparticles, as revolutionary nanomedicines, have offered a new class of
diagnostic and therapeutic solutions for a multitude of diseases. With its immense potential …

Introduction Poly (lactic-co-glycolic acid)(PLGA) has been used in many long-acting drug
formulations, which have been approved by the US Food and Drug Administration (FDA) …