Active matter, which ranges from molecular motors to groups of animals, exists at different length scales and timescales, and various computational models have been proposed to …
O Ilina, PG Gritsenko, S Syga, J Lippoldt… - Nature cell …, 2020 - nature.com
Plasticity of cancer invasion and metastasis depends on the ability of cancer cells to switch between collective and single-cell dissemination, controlled by cadherin-mediated cell–cell …
R Alert, X Trepat - Annual Review of Condensed Matter Physics, 2020 - annualreviews.org
Collective cell migration is a key driver of embryonic development, wound healing, and some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …
Pathological morphological changes in tumor tissue enable collective cancer cell unjamming, a cellular motility transition. However, fundamental questions remain: Is …
The epithelial-to-mesenchymal transition (EMT) and the unjamming transition (UJT) each comprises a gateway to cellular migration, plasticity and remodeling, but the extent to which …
S Grosser, J Lippoldt, L Oswald, M Merkel… - Physical Review X, 2021 - APS
Tissue, cell, and nucleus morphology change during tumor progression. In 2D confluent cell cultures, different tissue states, such as fluid (unjammed) and solid (jammed), are correlated …
H Mohammadi, E Sahai - Nature cell biology, 2018 - nature.com
The physical characteristics of tumours are intricately linked to the tumour phenotype and difficulties during treatment. Many factors contribute to the increased stiffness of tumours; …
A passive solid cannot do work on its surroundings through any quasistatic cycle of deformations. This property places strong constraints on the allowed elastic moduli. In this …
PF Lenne, V Trivedi - Nature Communications, 2022 - nature.com
Biological systems display a rich phenomenology of states that resemble the physical states of matter-solid, liquid and gas. These phases result from the interactions between the …