Spinal cord injury: molecular mechanisms and therapeutic interventions

X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - … and Targeted Therapy, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …

Trans-spinal electrical stimulation therapy for functional rehabilitation after spinal cord injury

MA Rahman, NS Tharu, SM Gustin, YP Zheng… - Journal of Clinical …, 2022 - mdpi.com
Spinal cord injury (SCI) is one of the most debilitating injuries in the world. Complications
after SCI, such as respiratory issues, bowel/bladder incontinency, pressure ulcers …

Using a high-frequency carrier does not improve comfort of transcutaneous spinal cord stimulation

AN Dalrymple, CA Hooper, MG Kuriakose… - Journal of Neural …, 2023 - iopscience.iop.org
Objective. Spinal cord neuromodulation has gained much attention for demonstrating
improved motor recovery in people with spinal cord injury, motivating the development of …

Combined transcutaneous electrical spinal cord stimulation and task-specific rehabilitation improves trunk and sitting functions in people with chronic tetraplegia

NS Tharu, M Alam, YT Ling, AYL Wong, YP Zheng - Biomedicines, 2022 - mdpi.com
The aim of this study was to examine the effects of transcutaneous electrical spinal cord
stimulation (TSCS) and conventional task-specific rehabilitation (TSR) on trunk control and …

Transcutaneous spinal stimulation from adults to children: a review

G Singh, K Lucas, A Keller, R Martin… - Topics in Spinal …, 2023 - meridian.allenpress.com
Neuromodulation via spinal stimulation is a promising therapy that can augment the
neuromuscular capacity for voluntary movements, standing, stepping, and posture in …

Multi-site spinal cord transcutaneous stimulation facilitates upper limb sensory and motor recovery in severe cervical spinal cord injury: A case study

P Sharma, T Panta, B Ugiliweneza, RJ Bert… - Journal of Clinical …, 2023 - mdpi.com
Individuals with cervical spinal cord injury (SCI) rank regaining arm and hand function as
their top rehabilitation priority post-injury. Cervical spinal cord transcutaneous stimulation …

[HTML][HTML] Safety and feasibility of cervical and thoracic transcutaneous spinal cord stimulation to improve hand motor function in children with chronic spinal cord injury

G Singh, A Keller, K Lucas, C Borders, D Stout… - … : Technology at the …, 2024 - Elsevier
Objective In adults with cervical spinal cord injury (SCI), transcutaneous spinal stimulation
(scTS) has improved upper extremity strength and control. This novel noninvasive …

Spinal Cord Epidural Stimulation Improves Lower Spine Sitting Posture Following Severe Cervical Spinal Cord Injury

K Joshi, E Rejc, B Ugiliweneza, SJ Harkema… - Bioengineering, 2023 - mdpi.com
Cervical spinal cord injury (SCI) leads to impaired trunk motor control, negatively impacting
the performance of activities of daily living in the affected individuals. Improved trunk control …

Spinal cord transcutaneous stimulation in cervical spinal cord injury: A review examining upper extremity neuromotor control, recovery mechanisms, and future …

G Singh, P Sharma, GF Forrest, SJ Harkema… - Journal of …, 2024 - liebertpub.com
Cervical spinal cord injury (SCI) results in significant sensorimotor impairments below the
injury level, notably in the upper extremities (UE), impacting daily activities and quality of life …

[HTML][HTML] Combining spinal neuromodulation and activity based neurorehabilitation therapy improves sensorimotor function in cerebral palsy

R Sachdeva, K Girshin, Y Shirkhani, P Gad… - Frontiers in …, 2023 - frontiersin.org
Motor dysfunction in individuals with cerebral palsy (CP) such as the inability to initiate
voluntary movements, walking with compensatory movement patterns, and debilitating …