[HTML][HTML] Neuroinflammation and Epilepsy: From Pathophysiology to Therapies Based on Repurposing Drugs

P Sanz, T Rubio, MA Garcia-Gimeno - International Journal of Molecular …, 2024 - mdpi.com
Neuroinflammation and epilepsy are different pathologies, but, in some cases, they are so
closely related that the activation of one of the pathologies leads to the development of the …

[HTML][HTML] The contribution of microglia and brain-infiltrating macrophages to the pathogenesis of neuroinflammatory and neurodegenerative diseases during TMEV …

AB DePaula-Silva - Viruses, 2024 - mdpi.com
The infection of the central nervous system (CNS) with neurotropic viruses induces
neuroinflammation and is associated with the development of neuroinflammatory and …

[HTML][HTML] Neuroinflammation and status epilepticus: a narrative review unraveling a complex interplay

T Foiadelli, A Santangelo, G Costagliola… - Frontiers in …, 2023 - frontiersin.org
Status epilepticus (SE) is a medical emergency resulting from the failure of the mechanisms
involved in seizure termination or from the initiation of pathways involved in abnormally …

Neuropathology of new-onset refractory status epilepticus (NORSE)

A Hanin, J Cespedes, A Huttner, D Strelnikov… - Journal of …, 2023 - Springer
Abstract New-Onset Refractory Status Epilepticus (NORSE), including its subtype with a
preceding febrile illness known as FIRES (Febrile Infection-Related Epilepsy Syndrome), is …

Palmatine attenuates LPS‐induced neuroinflammation through the PI3K/Akt/NF‐κB pathway

J Zeng, H Pei, H Wu, W Chen, R Du… - Journal of Biochemical …, 2024 - Wiley Online Library
To investigate the key molecular mechanisms of palmatine for the treatment of
neuroinflammation through modulation of a pathway using molecular docking, molecular …

mTOR and neuroinflammation in epilepsy: implications for disease progression and treatment

T Ravizza, M Scheper, R Di Sapia, J Gorter… - Nature Reviews …, 2024 - nature.com
Epilepsy remains a major health concern as anti-seizure medications frequently fail, and
there is currently no treatment to stop or prevent epileptogenesis, the process underlying the …

Mechanisms and Emerging Therapies for Treatment of Seizures in Pediatric Autoimmune Encephalitis and Autoinflammatory/Autoimmune-Associated Epilepsy

MM Andzelm, CM Stredny - Rheumatic Disease Clinics, 2023 - rheumatic.theclinics.com
Although first proposed over a century ago, 1, 2 in the past few decades, there has been an
increasing appreciation of the role of the immune system and inflammation in a Program in …

[HTML][HTML] Pharmacological elevation of glutathione inhibits status epilepticus-induced neuroinflammation and oxidative injury

LP Liang, AS Hari, BJ Day, M Patel - Redox Biology, 2024 - Elsevier
Glutathione (GSH) is a major endogenous antioxidant, and its depletion has been observed
in several brain diseases including epilepsy. Previous studies in our laboratory have shown …

[HTML][HTML] A Systematic Review of the Predictive and Diagnostic Uses of Neuroinflammation Biomarkers for Epileptogenesis

MJ Aguilar-Castillo, P Cabezudo-García… - International Journal of …, 2024 - mdpi.com
A central role for neuroinflammation in epileptogenesis has recently been suggested by
several investigations. This systematic review explores the role of inflammatory mediators in …

Do vaccines cause epilepsy? Review of cases in the National Vaccine Injury Compensation Program

RC Scott, SL Moshé, GL Holmes - Epilepsia, 2024 - Wiley Online Library
Abstract Objective The National Childhood Vaccine Injury Act of 1986 created the National
Vaccine Injury Compensation Program (VICP), a no‐fault alternative to the traditional tort …